The blockbuster weight loss drug sold as Ozempic and Wegovy [has, on 21 March, gone] generic in countries that are home to 40 percent of the world’s population, significantly lowering the price of a costly medicine that had been largely unaffordable to nearly all but the wealthiest people. On Saturday, Novo Nordisk, the company that until now has had a monopoly on selling the drug, will lose patent protection in several of the world’s most populous countries. The first generic versions are expected to arrive in India as soon as this weekend. In the coming months, the generics are also expected to become available in China, Canada, Brazil, Turkey and South Africa.

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[–] 4 points 7 months ago

In New Delhi, Dr. Nivedita Dadu, a dermatologist, said she expects patient demand for the drugs to grow once cheaper generics become available. Already, she and her sister, an anesthesiologist, have been prescribing the brand-name drugs to hundreds of patients.

Why the f*** are a dermatologist & an anaesthetist prescribing weight-loss drugs to people???

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  • [–] -2 points 7 months ago (1 child)

    People really will do anything besides eat fiber...

    Even after the we know about all the downsides of this stuff

    The reason the floodgates are opening like this, is one last cashgrab. It's not the miracle drug people thought

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    [–] 82 points 7 months ago (11 children)

    Ok so how can I get generic ozempic from India, because here in the US there probably won't be a generic until at least 2032 due to how our patent laws work.

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  • [+] 11 points 7 months ago (4 children)
  • [–] 36 points 7 months ago (3 children)

    Yes, my understanding is that it's legal in the US to purchase prescription-only drugs from overseas as long as they're only for personal use. It's kind of a grey area but as long as they're not scheduled substances, I and multiple people I know have saved a lot of money by buying prescription drugs from Europe and shipping them here (we have such a wonderfully broken system here, don't we?)

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  • [–] 17 points 7 months ago (2 children)

    If you go to border towns in Mexico like Tijuana they have pharmacies on every corner like Starbucks where you can buy medications.

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  • [–] 5 points 7 months ago (3 children)

    I’ve purchased generic medications on DNMs before. There was a user “Indiapilldaddy” who sold hundreds of different generics. Antibiotics, antivirals, cholesterol, blood pressure, etc. With the review system on the DNMs it’s probably more trustworthy than some random website that pops up.

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  • [+] 20 points 7 months ago (-1 children)
  • [+] 9 points 7 months ago
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  • [–] 1 point 7 months ago (-1 children)

    The rest of the world doesn't need Ozempic.

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    [–] 10 points 7 months ago (4 children)

    We're not able to regulate the food and automobile industry so we're going to drug everyone forever so that we don't end up like the Pixar spaceships. In 20 years we'll discover the side effects and everyone will be shocked.

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  • [–] [S] -3 points 7 months ago (2 children)

    i believe cravings can make one obese even if ze only selects foods that ze can make in zir own kitchen

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  • [–] 22 points 7 months ago* (28 children)

    Here comes a gentle reminder: Ozempic is primarily meant as a medicine for type 2 diabetes and non-alcoholic fatty liver disease. It has plenty of side effects, does not lead to long-term weight loss and may harm you in the long run. It may be helpful, but it shouldn't be taken uncontrollably.

    Consult your physician to determine if it's the best way forward.

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  • [–] 7 points 7 months ago

    I've been on it for 2 years for weight loss/maintenance and it's life-changing & I wish this existed 30 years ago, my entire life & self-esteem would've made me a completely different person so much more confident & goal-achieving

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  • [–] 3 points 7 months ago (4 children)

    Lost my best friend of 20 years and I blame this drug. I am convinced rapid weight loss when you've been fat for 35 years is going to be a huge change to the brain as well. Dude isn't the same person anymore

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  • [–] 1 point 7 months ago (3 children)

    I assumed your friend died from the first sentence, care to elaborate?

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  • [–] 5 points 7 months ago* (last edited 7 months ago) (2 children)

    After losing half of his weight he ghosted me and I haven't heard from him in 2 years now.

    My best theory is he got female attention for the first time in his life and he subconsciously wrote me off as useless to him now. He got strung along by a couple of girls and he didn't like my opinions on any of that and kind of just got rid of me.

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  • [–] 3 points 7 months ago (1 child)

    damn that's sad, I have seen this thing happening with people losing weight in general. not like they all turn our like your friend but some of them just behave a certain way due to lack of self-esteem.

    no wonder i guess, people usually don't treat you like a person if you are overweight, and then having all that attention went over his head probably

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  • [–] 3 points 7 months ago* (last edited 7 months ago)

    Yeah it was actually chatgpt that tossed me this theory and it makes perfect sense. I don't think ozempic itself destroyed his brain. It was just the rapid weight loss in general which was only possible due to ozempic. Dude went from like 350 to 200 so fast.

    Basically said he only kept me around because I was a loser like him and now he thinks he's better than me. I think this nails it.

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  • [–] -3 points 7 months ago* (last edited 7 months ago) (21 children)

    People don't care. They just want to lose weight with zero effort.

    Already have had friends of friends and family who have been on it, lost 30-40lbs, and went off it, and gained it all right back. It's basically the yo-yo dieting in prescription form.

    Most of my friends and family are skinny and healthy and have never gained much weight beyond temporary gains... how? Diet and Exercise. But I def regular encounter that basically think diet and exercise can't possibly be the solution to their weight issues... while they suck down 40oz sugar coffees everyday and are winded by walking .5km

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  • [–] 3 points 7 months ago (19 children)

    What would you say to someone who weighed about 28.5 stone, suffers with chronic lower back pain that limits movement, inflammation causing limited range of motion caused by the excessive weight, knee problems which limit ability to climb stairs and do things like squats or stand from kneeling or from the floor who eats uncontrollably to get a dopemine fix because they cant get adhd medication because of NHS wait times and lack of in person clinics, which are needed due to hypertension and irregularities on ana ECG and doesnt self medicate with weed anymore due to legality l, access and health issues.

    Can't exercise effectively due to weight, can't lose weight to get help with excessive eating due to inability to exercise effectively. Catch 22. I am fucked.

    Do i not qualify as having a legitimate reason to take weightloss medication to get me into a place where i can move properly. My quality of life is shit and i have done everything to try to fix it. I have an exercise bike but cant use it for long due to pain in my knees and shins, started swimming to ease the load on my knees but couldnt get any room in my local pool to exercise due to lane swimmers, all the dedicated classes take place whilst i am in work or too close to my finishing times. I need to travel 40 minutes to a pool that does a class at the right time for me. Have kids and house to help with. I took a weightloss course with NHS but lost nothing because it was a pile of crap course that didnt adress the issues people have with weight and only told us all what we already knew and offered a single 40 minute class a week doing low impact exercises in 2 minute bursts.

    I started taking mounjaro which i pay out of my arse for, and i have lost 2 stone so far. On track to lose even more. Starting to exercise again. Feel better overall. Cardio is better, can walk further than 30 metres without needing to sit down. Back pain is still here but hopefully will ease off.

    Ive never been this big in my life, always a bit chunky (like 14-16 stone in my teens to early 30s) stopped smoking and piled it on over a year.

    Its not so black and white.

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  • [–] -3 points 7 months ago (18 children)

    I'd question your mental health.

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  • [–] 3 points 7 months ago

    Ok so putting aside the fact that i talked about having ADHD and it being a big contributor to my eating habits. I list a bunch of physical health problems and how they dorectly impact my ability to lose weight and you question my mental health?

    I think its clear that in terms of mental health, you are the one with problems. You are narrow minded, you have a bit of a god complex based on your other comments in this thread, you are arrogant and seemingly ignorant to all of it. What kind of person does it take to give a bad opinion, have that opinion challenged with genuinely good points but still turn around and "no you" it back to me?

    The only thing your comment fails to address is everything i said. Its clearly unintelligent, backing down, goalpost moving trash.

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  • [–] 2 points 7 months ago (8 children)

    everything I want to say to you will be removed

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  • [–] -2 points 7 months ago* (7 children)

    exactly. if that's your impulse... you probably need some better mental health habits and emotional regulation.

    I have my own health problems. I am not here blasting other people about them and how horrible and unfair my life is because of them... why is that you think?

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  • [–] 3 points 7 months ago (6 children)

    because you don't care for other people but will whine about other people not caring enough to lose weight

    nobody is here "blasting" you they are speaking from their own experience with weight loss and all you had to say was to question their mental health

    yeah i lack emotional regulation, like that's a thing for me and people with my condition, at least i know my faults

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  • [–] 0 points 7 months ago (5 children)

    I don't care for random internet strangers and people in the vague abstract mass of humanity, yeah. It's fucking weird that anyone thinks that is legitimate caring. It isn't. It's just a proxy for grand standing and ego-stroking.

    I don't care about their experience. It has no impact on what is a massive public health issue. The world is not about them and their individual experiences. And their inability to see usually means they are a egotistical nutjob who thinks everything is about themselves and their personal feelings... which actually is the type of people who give a shit about nobody but themselves.

    Randomly going into vivid detail abut all your personal problems to vent at some stranger you feel has aggrieved you in a public space is insane and hostile behavior. I'm sure if I randomly went up to you and started screaming at you about my personal health issues, you'd find that very offputting and offensive and you'd wonder if I was off my meds.

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  • [–] [S] 1 point 7 months ago (2 children)

    or, perhaps, they wanted to show you a different perspective you do not know without aggression

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  • [–] 0 points 7 months ago* (last edited 7 months ago) (1 child)

    I've met tons of whiny people my entire life who write essays about their problems. I don't need to hear from more of them. I understand lemmy is full to the brim with them though, who have delusions of grandeur because they PC game with linux or something, and yet they can seem to struggle with basic adult tasks. weird how that works.

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  • [–] 1 point 7 months ago

    There is nothing hostile about challenging your narrowmindedness with anecdote. You don't need to care about every living being on this planet to understand that you can't just pull a one size fits all blanket over a problem to make it go away.

    There is nuance, individual expereince does matter when discussing public health issues. Your statement about people being too lazy to make the effort is clearly misjudged. The fact that i am one example of evidence of that does not mean i think its all about me. Seriously, you are out of touch.

    It is funny that you address everyone here, talking about me, except for me. The person you are talking about.

    Why don't you have this conversation with me?

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  • [–] 1 point 7 months ago

    it's weird that you think that is just egostroking, that's where we differ

    and you would be amazed by town hall meetings! it is exactly as you said! random people you don't know come in a public space to share their grievances and complains

    but hey, if you don't care about their experience then why should i care about anything you say? im out!

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  • [–] [S] 1 point 7 months ago* (7 children)

    you do realize he mentions ADHD? i'm sure you don't mean to but your comment implies the mentally ill can just pull themselves up by their bootstraps

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  • [–] 0 points 7 months ago (5 children)

    Then treat it.

    I am more than familiar with people like him. I have had relationships with people who made endless excuses, and refused to manage their conditions, and then of course, told me it was my fault. As if I was supposed to magically cure them of all their mental and physical issues... that they actively embraced and enhanced by poor habits and recreational drug use.

    When it comes to mental and physical health, yes you do have to pull yourself up. Nobody can do it for you. Nobody can fix my health problems for me. It's my responsibility to manage them. Or I suppose I could just give up, and be a twat about it and incessantly whine to whomever will listen to my self-imposed misery. And go around taking random internet comments as personal attacks on myself... lol

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  • [–] 3 points 7 months ago

    Read my post properly and you might see why treating it is a problem.

    You need to stop ignoring the bits that counter your argument because it is making you look ignorant.

    And i can't get over that whole point you are trying to make about people (me in this case) making it all about themselves when you are doing exactly that. You are imposing your narrowminded and ignorant view poi t on everyone else. Hilariously, no one agrees. You are on your own on this one.

    Please do us all a favour. Read and critically analyse this comment thread. Be self critical, look at it from a view point that is not your own. And understand that my offering a personal anecdote, in contrary to your view is not "an attack" it is not me taking your nonsense as a personal attack on me. It is just me trying to introduce some nuance. Something you may not know.

    Isnt the point of these message boards to have discussions with real people from around the world? Are you really on a social media platform pretending you don't care what other people think?

    Wild that mate.....

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  • [–] 2 points 7 months ago (2 children)

    don't worry nobody here is taking anything as a personal attack, you just repeat ableist rhetoric that is used to attack anyone with a handicap and i want to make that clear for anybody else reading it

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  • [–] -3 points 7 months ago*

    Individual differences matter.

    Some people are eating like a truck and can barely be called active, yet remain slim.

    Some others put a much greater effort into keeping themselves in shape, stick to a diet, exercise a lot, and still don't have it.

    There are plenty of genuine issues that can make losing weight problematic. But taking random drugs without prescription like there's no tomorrow is not going to help.

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  • [–] 5 points 7 months ago* (last edited 7 months ago)

    edit: man imagine being angry that a drug has gone generic so more people can benefit from it, i hope all you removed and removed

    I hope it comes soon here, I'm prediabetic and was starting to be unable to hold myself up for more than 5 minutes without a sharp pain in my back that made me unable to do a lot of things (except work of course)

    Right now I'm on fentermine and it helps my audhd but the main effect is that now I don't feel the urge to eat huge volumes of food just to feel "good" and bloated for the next 4 hours. I already lost 10 kilos and it let me start exercising. Good shit but I'm already on the last half of my treatment

    I hope no-one is in a position where their own body betrays them with a chemical imbalance that leads them to not make the best decisions for their health, because after reading some comments some of you would commit suicide before taking any "stupid pill"-

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  • [–] 2 points 7 months ago

    Never believe it's not so

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  • [–] 2 points 7 months ago* (last edited 7 months ago) (1 child)

    i tried it briefly for a couple months, got embarrassed at myself for my brief moment of insanity that I had tried it and stopped.

    observing all this is beyond my ability to any longer have sympathy for the human race as a whole . Instead of banning cars, starbucks and fast food etal we design a drug to sell to you.

    Like many of the endless examples of human stupidity, it seemingly makes lots of sense at an individual level and is completely fucking insane at a societal level.

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  • [–] 1 point 7 months ago

    If you look at photos and footage from like 50 years ago, everyone was way thinner. I don't believe we've just got greedier. I don't believe people were necessarily choosing healthier options. The food has changed and is practically poisonous. People don't want to be this way and I don't think it's fair to blame them directly.

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  • [+] -11 points 7 months ago (18 children)
  • [–] 37 points 7 months ago (10 children)

    isn't it meant to be a permanent treatment?

    no one says insulin is inefficient because diabetics die if they stop taking it.

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  • [–] 10 points 7 months ago (5 children)

    Exactly. And these drugs were originally diabetes medications. And they don’t cure diabetes.

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  • [–] 3 points 7 months ago (3 children)

    Not directly.

    But borderline people who lose a lot of weight can sometimes get into the range of non-insulin-dependent life.

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  • [–] 3 points 7 months ago* (last edited 7 months ago) (2 children)

    that's type 2 and early stages.

    i hope that my example made it clear I didn't mean those cases.

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  • [–] -2 points 7 months ago (2 children)

    sorry but some people do say it's inefficient and unfair. insulin is not free (not in all countries at least) and it's extra effort and task management which is forced on people, some of them just because they were born with diabetes and never had a choice.

    it's like a tax for being born a certain way.

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  • [–] 1 point 7 months ago (1 child)

    insulin is practically free to make, is about a couple $ per month without subsidies.

    If you pay more than that it is a literal scam and people belong in jail.

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  • [–] 8 points 7 months ago (2 children)

    This drug isn't the solution: it's a band-aid to give people more time to develop better habits.

    Many people will not - sometimes they believe they can merely get back on the drug when their lifestyle starts killing themselves again.

    The drug will drop the weight, though. But, like dialysis, it's not a permanent treatment, nor is it a fix.

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  • [–] 13 points 7 months ago* (1 child)

    imo the fact the drug works as well as it does is more evidence that the problem is better conceptualized as physiological than psychological. If someone's body insists to them, wrongly and chemically, that they are starving, that's the real problem because making decisions with chemicals is what our brains do, and we evolved to have less direct agency over the things that most directly impact our survival.

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  • [–] 2 points 7 months ago

    I took Ozempic for awhile until I left the US it was amazing simply for the fact it just curbed my constant hunger. I was always ALWAYS hungry. I would literally eat til full and then still feel hungry. I went on a big diet for awhile to manage portions and generally eat healthier but the hunger just distracted me constantly and kept me from sleeping. I was on the diet for the better part of A year and I never got used to the portion sizes (I did get used to eating better food though)

    then I finally started taking Ozempic and when the hunger started subsiding I felt so much better. My type II was able to be managed much more effectively so I actually had energy. I slept better, I worked better and could think clearer. It was actually life changing and I did start losing weight.

    Now im in a country where its not as accessible if at all and even if it was available, I make so little money I probably cant afford it. I used my last two doses while I was here and then just went off it. The hunger is back and my blood sugar is back to being not so controlled. Im eating more because of the hunger and if I dont I get very grumpy and unpleasant to be around. Im tired and exhausted all the time. I am doing a little better than before because good healthy food is easier and cheaper to come by. Im also much much much more active whether I like it or not but it is keeping the pounds off so im definitely burning all the calories that I am eating at least but being so active and hungry is even more miserable.

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  • [–] 15 points 7 months ago

    I think you need to make permanent changes to lifestyle and eating to keep weight off. If you return to your old ways then the weight comes straight back on. Just like a crash diet.

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  • [–] 4 points 7 months ago*

    The point is to help a person get used to eating a lot less, and when they hit their target weight, they can continue with their new eating habits.

    But if you go back to the same eating habits that made you fat, you're gonna get fat.

    I've dropped 100 pounds over about 3 years (and still dropping), without any drugs, because I taught myself to get by with much smaller portions. Partially it came from eating only when hungry, not bored.

    The other, possibly more important thing was using a distraction, so when I'm tempted to go see what's in the fridge, I pick up my guitar instead. So I've lost a lot of weight, AND learned to play the guitar at the same time. Replacing a bad habit with a good one is very effective.

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  • [+] 4 points 7 months ago
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  • [–] 6 points 7 months ago (-1 children)

    I believe they work by lowering your appetite, generally leading to less eating, especially snacking.

    Even liposuction, literally taking the fat out of the body, doesn't result in permanent weight loss.

    What do you expect a drug to do to make you skinny without it needing to become something you take regularly? If you want to lose weight permanently, you have to work for it, no matter which strategy you use.

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  • [+] 1 point 7 months ago
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  • [–] 1 point 7 months ago (-1 children)

    There are the structural things - removing parts of the intestine, installing restrictive bands around the stomach.

    Both of them require a surgery and can have HUGE complications. Oh yeah and they are not a permanent solution, just as ozempic they just help to start developing better habits, you will regain weight after sometime if you don't keep a better diet even with these procedures

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  • [+] 1 point 7 months ago
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  • [–] 1 point 7 months ago (-1 children)

    Of course if you’re determined to live a life of gluttony, these things are all temporary - even more temporary than life itself.

    You could just not assume that? It's not about determination, as you said, it is an addiction. The root cause is not a food addiction, we literally need food to survive, but that root cause is different for every person and unless you are that same person you just don't assume shit about intentions or determination.

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