Terminator 2 uses identical twins twice. Once when T1000 copies the cop drinking coffee and later when the T1000 copies Sarah Connor.

This is not uncommon with twin child actors. The Olsen twins in Full House are a famous example

Ever seen The Prestige?

There's a series on Disney+ called "Pixar in Real Life". It's like candid camera, getting random people to react to strange stuff. They had a kid dressed as Dash from The Incredibles ask random people to time him running around a large building and surprising them by doing it impossibly fast. It was actually identical twins

Aaron and Shawn Ashmore are twin actors, I know that although Aaron actually played both of a set of twins in My Brother’s Keeper, Shawn is actually in some scenes.

It was more of a special effects shortcut, but it’s twins playing twins, so I don’t know if that counts!

The scene is far away. I don't think you need twins for that. Being the same complexion plus some context to explain to the watcher that those are the same person would suffice.

Orphan Black: Live

Spoiler, but twins figure prominently in Christopher Nolan's film The Prestige.

Would it be an error to make it a comedy?

Nothing in your example requires two actors.

"Best we can do is The Parent Trap. 🤷‍♂️"