Maybe with a small penalty
Small penalty is when you make a mistake. Gigantic deductions with no income would have them charging you with tax fraud. The lawyer fees to defend yourself would be worse than the penalties.
Lack of profit doesn't mean a business is unsuccessful
Companies like Amazon showed losses a decade because they had income from investors. So they had income, it was only that the "business" side of the business was unprofitable.
You can't get away with deducting your mortgage as a business express from a unprofitable garage sale. Certainly not year after year.
Why do you assume you won't find a profitable niche in the process?
So we are back to, "just buy a house if you can't afford rent."
Tax avoidance schemes isn't the argument.