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[–] 69 points 8 months ago (10 children)

tl;dr: we don't know yet.

If I had to guess, I'd say microplastics or some dietary thing like aspartame.

But there's also a link between colon cancer and running. The article mentions two people as pictures of health who run a lot.

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  • [–] 18 points 8 months ago (3 children)

    We don't know yet, but the article mentions it's likely that the gut microbiome is involved, which means microplastics and food additives are unlikely to have much of an importance.

    There are plenty of pathogens that cause cancers, and the article implies something about our lifestyle or their own evolution has turned a formerly benign entity against us.

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  • [–] 4 points 8 months ago (1 child)

    My bet's on Long COVID. It's been connected to so many other random medical issues popping up (including diabetes, low sperm counts, and early onset Alzheimers IIRC) that it may as well be connected to ass cancer as well.

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  • [–] 33 points 8 months ago (15 children)

    Men in their 20s, 30s, and 40s—runners, CrossFitters, lifelong nonsmokers—were streaming through her door at the Dana-Farber Cancer Institute. They all appeared lively and strong—yet there they were, battling colorectal cancers

    Well there's your problem. Don't run, drink beer with friends, smoke socially and you'd happily get to retirement! 🤭

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  • [–] 20 points 8 months ago (13 children)

    Perhaps overconsumption of protein?

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  • [–] 17 points 8 months ago (11 children)

    Same thought i had. A lot of men nowadays eat almost no fibre, which is very important in preventing colon cancer.

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  • [–] 4 points 8 months ago (1 child)

    That's why I also drink Metamucil twice a day. Stuff is fantastic for keeping everything moving. And I eat my fruits and veggies, but nothing wrong with a little supplementation.

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  • [–] 1 point 8 months ago (6 children)

    Naa, humans consume a lot more fiber than in the past. Salted meat was basically one of the main things we were able to store for long periods of time. The one thing that has changed? Overeating and sedentary lifestyle.

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  • [–] 2 points 8 months ago (5 children)

    I get that i said nowadays but the comparison is irrelevant because whether they're consuming more or less than in the past, it's still not enough. Also a lot has changed, including capitalism taking away our time, thereby forcing a lot of people into convenient, cheap options.

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  • [–] 2 points 8 months ago (4 children)

    Most people in the past worked just to be able to eat. It's way easier to get food now than ever. This isn't a capitalism thing, this is consumerism and being to lazy to cook home food. It's way cheaper to eat grocery store bought food you prep and cook for yourself than it is to eat fast food. That shit is expensive as fuck.

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  • [–] 1 point 8 months ago (3 children)

    The ever increasingly pressure capitalism is putting on people is causing a lot of issues.

    People are overworked, overstressed just to make through the end of the month and that causes a lot of issues. It's reductive to blame people not cooking solely on being lazy.

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  • [–] 1 point 8 months ago (2 children)

    No it is not

    https://pubmed.ncbi.nlm.nih.gov/40310280/

    The Netherlands works some of the shortest hours in the world, has some of the best healthcare, and also has a rise in CRC. This is not a capitalism bad argument. This is a change in our society, and potentially a "microplastics are everywhere now". This has nothing to do with capitalism bad.

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  • [–] 1 point 8 months ago (1 child)

    I was talking about your "people are lazy" comment, not the colorectal cancer rise in men.

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  • [–] 1 point 8 months ago*

    People are not wanting to cook, this is not a "they have no time". They don't cook because fast food is easier.

    We live in a consumerism society, which so many have gotten used to. It's why if this society collapses, starvation is going to be off the charts. People don't know how to survive anymore without instant meals and premade food.

    https://www.bonappetit.com/entertaining-style/trends-news/article/michael-pollan-cooked-netflix-show?srsltid=AfmBOopdccaXwIbodgKhLekOy1kQMeaOITBvGdTJQA3-Hj93IRWUUNwf

    You also pointed out that they don't have time. Which I provided with evidence that the rise of CRC is hitting the Netherlands just as bad, and they have some of the best work/life balance on the planet.

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  • [–] 1 point 8 months ago (1 child)

    How does fiber prevent colon cancer?

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  • [–] 8 points 8 months ago

    https://pmc.ncbi.nlm.nih.gov/articles/PMC10488173/

    "Colorectal cancer (CRC) is one of the leading causes of mortality for cancer in industrialized countries. The link between diet and CRC is well-known, and presumably CRC is the type of cancer which is most influenced by dietary habits. In Western countries, an inadequate dietary intake of fibers is endemic, and this could be a driving factor in the increase of CRC incidence."

    Fiber prevents colon cancer primarily by increasing stool bulk and speeding up transit time, which reduces the contact between harmful carcinogens and the colon lining. It also acts as food for beneficial gut bacteria, fermenting into short-chain fatty acids like butyrate that reduce inflammation and promote cancer cell death.

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  • [–] 4 points 8 months ago

    Distance running has been scientifically linked to an increase in colon cancer rates, and CrossFit could easily be similarly unhealthy as far as inducing extra stress on the intestine by being an activity that can lead to dehydration while violently shaking things around in there more than what could be considered "normal."

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  • [–] 24 points 8 months ago (1 child)

    Not enough fiber. Everyone eating carnivore diets and nobody eating fibrous foods

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  • [–] 24 points 8 months ago* (last edited 8 months ago) (1 child)

    F. nucleatum animalis. Cancer causing bacteria. No l, there's not much you can do. Results of the 2024 study by Nature.

    https://www.cancer.gov/news-events/cancer-currents-blog/2024/colorectal-cancer-fna-c2-bacteria

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  • [–] 67 points 8 months ago* (11 children)

    Mine went from zero to stage 2 in 6 months, no family history, no genetic pre-disposition. Surgery 1 week from today.

    March is colon cancer awareness month, get checked and wear blue.

    Pro-tip, the stuff they make you drink before hand is NASTY. It tastes like salt water and not even GOOD salt water, salt water made with that fake potassium salt.

    But if you add Gatorade powder (lime or arctic cherry, green or white drinks only, no orange or red) it's drinkable. One glass every 12 minutes for 2 hours, wait 6 hours and do it again:

    .

    Colonoscopy itself is no big deal, you're out for the whole thing!

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  • [–] 25 points 8 months ago (2 children)

    When I did mine I made the mistake of trusting a fart... Don't trust your farts while taking this

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  • [–] 6 points 8 months ago (2 children)

    Colonoscopy itself is no big deal, you’re out for the whole thing!

    I mean if you're in pain, sure, do it.

    Otherwise I recommend staying awake (do ask your doctor though). I had a blast looking so deep inside me, but I had no issues (like tumors or inflammation) and the awful drink actually cured my constipation (the chronic constipation being the reason why I had colonoscopy in the first place).

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  • [–] 6 points 8 months ago (1 child)

    If it had JUST been a colonoscopy, yeah, but they wanted an endoscopy as well ("Oh, a spit roast!" - "Don't call it that!")

    I've had so many medical things done that I always opt to be out when possible.

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  • [–] 3 points 8 months ago*

    I had an endoscopy (gastroscopy is the word I think?) once (tube from the front and they took something for biopsy) and I cried and gagged with snot during the whole procedure. I concur, I'd rather be out next time I have to have it.

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  • [–] 4 points 8 months ago (1 child)

    Sorry to hear. Best of luck!

    How did you find out?

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  • [–] 5 points 8 months ago

    Was struggling with anemia, low energy, out of breath, blood panels showed low hemoglobin, poor red blood cell counts, small and irregular red blood cells.

    Something was chewing up all the red blood cells. Had a colonoscopy / endoscopy ("Oh, so a spit roast!" - "Don't call it that!") and they found 17 polyps. 2 were abnormally large (>5mm) one was 20mm, one 30mm.

    No cancer though, wanted to re-do in January.

    Went back, 6 more polyps, one 20mm + stage 2 cancer.

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    [–] 16 points 8 months ago (5 children)

    Definitely need more research. I was diagnosed at 36 and had no genetic predisposition. Doc said I was just "unlucky."

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  • [–] 3 points 8 months ago (4 children)

    What prompted you to get checked?

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  • [–] 8 points 8 months ago (3 children)

    There were two symptoms. My stool started to get smaller in diameter because the tumor was squeezing the colon, and I started to have abdominal pain because the tumor attached itself to the inner lining of my abdomen.

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  • [–] 4 points 8 months ago (2 children)

    Thank you for sharing, I appreciate you.

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  • [–] 3 points 8 months ago (1 child)

    You're welcome! I'm always happy to answer questions about it. Get checked out if you have any symptoms whatsoever.

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  • [–] 5 points 8 months ago

    I've pretty much always had digestive issues, but then again I've pretty much always had anxiety. I've gotten a lot better at differentiating my anxiety from actual issues, but a large part of that journey has been talking to doctors and getting tested for things... And then them inevitably telling me everything seems fine 😅

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  • [–] 10 points 8 months ago (2 children)

    Let me guess it's all the "food" we eat

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  • [–] 4 points 8 months ago* (3 children)

    I'm curious if as kids they loved the sour candy stuff popular during their youth, could there be a connection or correlation?

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  • [–] 11 points 8 months ago (2 children)

    Is there a reason you're jumping on sour candy specifically here?

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  • [–] 2 points 8 months ago*

    Ok, not op, but hear me out.

    Sour candy is typically flavored with various acids citric, malic, tartaric, etc. to achieve the sour taste.

    If the bacteria is normally in the mouth, but not typically able to survive the acidic environment of the gut, maybe that additional acid from sour candy was able to add selective pressure, and the surviving bacteria were then less affected by stomach acid.

    MAYBE

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  • [–] 3 points 8 months ago

    If youre nervous about colonoscopies there are alternatives out there. Tests like Cologuard are much less invasive. They are not 100% accurate, but something is better than nothing when it comes to colon cancer.

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  • 5 comments in c/health@lemmy.world view that post
    [–] 2 points 8 months ago (2 children)

    As long as it’s not getting railed up there causing it, I’m happy.

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  • [–] 2 points 8 months ago (1 child)

    https://www.cancer.gov/news-events/cancer-currents-blog/2024/colorectal-cancer-fna-c2-bacteria

    Over the last decade, one such species, called Fusobacterium nucleatum, has been strongly implicated as a potential contributor to colorectal cancer growth. Although F. nucleatum is normally found in the mouth, studies have also found increased numbers of it in the intestines of people with colorectal tumors compared with people without cancer.

    No analingus.

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  • [–] 2 points 8 months ago* (1 child)

    Good article. I remember reading one from a major publisher that basically said "we don't know", which is nonsense.

    One of the most intriguing leads is the microbiome, the diverse, teeming community of microorganisms living within us. Among the few things we know is that it’s constantly evolving. Some changes could “result in a benefit or insult to surrounding cells,” notes Dana-Farber physician and scientist Marios Giannakis, M.D., Ph.D. That means the microbiome may affect cells it touches and possibly play into the development of disease.

    Researchers are looking into anything that could be changing the microbiome and affecting these cancers. Right now they know that what you eat and what meds you take are at least part of it. Killing off bacteria with antibiotics can upset the microbiome’s balance. So may eating too much added sugar. (Aim for 36 grams a day max for general health.) “With anything that modulates the microbiome,” says Dr. Giannakis, “there’s an open question as to whether it’s good or bad. We just don’t know yet.” A new five-year, $25 million study led by Dana-Farber researchers aims to tease out some answers.

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  • [–] 2 points 8 months ago

    If the comment in the article is correct that this affects those with a healthy diet (presumably as well as that without), that leads me to wonder if high protein intake might be a factor as well. Or highly processed meats like deli meats and bacon. Men do tend to have a higher protein diet than women do, so it could help to explain the gender imbalance.

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