Kim Polk was 51 when she was diagnosed with ovarian cancer.
“I didn’t think I would live to be 60,” Polk said.
It was 2009 when doctors told her the cancer was stage three.
“When the doctor told me there was a six percent survival rate, I thought, you know, I’m done for,” Polk said.
But Polk fought it, and today, she’s here to tell her story.
“Here I am, 15 years later. And I’m healthy as a horse,” Polk said.
Polk had a hysterectomy and received chemotherapy, including a chemo infusion clinical trial at a hospital in Colorado.
Then, in 2012, Polk, who lives in Wyoming, heard about a phase one clinical trial happening at the University of Washington in Seattle.
“So my husband and I booked a flight and we went, and that’s how I got into it,” Polk said.
The trial was for an experimental cancer vaccine that targets ovarian cancer.
“What this vaccine is aimed to do is to eradicate any cells left in your body that have that malignant potential,” said Dr. Nora Disis.
Disis is director of the Cancer Vaccine Institute at UW Medicine, which has been a pioneer of researching cancer vaccines.
"The vaccine has already been through earlier trials, where the results were quite promising for preventing disease recurrence. So this trial is formally asking that question," Disis said.
They’re now entering a second phase of a clinical trial for an ovarian cancer vaccine, similar to the one Polk took part in. This phase is specifically seeking ovarian cancer patients who are in remission, among other factors.
The vaccine targets a specific protein linked to ovarian cancer cells.
“The way that the vaccine works is it starts the immune response at that protein, but creates a commotion in the tumor that causes the immune response to extend to other immunogenic proteins that are expressed in the cancer,” Disis said.
That protein, known as CA 125, is one of the strongest indicators of ovarian cancer cells, according to Disis. The vaccine being researched enables the body’s immune system to attack that specific protein and stop the cancer from coming back.