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[–] 116 points 9 months ago* (last edited 9 months ago) (26 children)

How the Therapy Works

The process involves regenerative medicine, utilizing the patient's own body's capabilities to treat the illness.

Cell Extraction: A small sample of cells (e.g., fat cells or blood cells) is taken from the patient. Reprogramming: These cells are chemically treated in a lab to revert them to a pluripotent state, meaning they can develop into any type of cell.

Differentiation and Transplantation: The stem cells are then guided to become functional, insulin-producing islet cells. These new cells are then transplanted back into the patient's abdominal area.

Restored Function: Once implanted, the cells engraft and begin producing insulin naturally in response to blood glucose levels, effectively restoring the body's natural ability to regulate blood sugar.

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  • [–] 29 points 9 months ago (5 children)

    That doesn't make sense for type 2. This is exactly how they've been trialing treatment of type 1, they just announced it a few months ago I think it was Stanford and Toronto

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  • [–] 2 points 9 months ago (4 children)

    Insulin producing cells die off in type 2 after years of being bombarded with sugar in the US diet.

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  • [–] 1 point 9 months ago (3 children)

    It's important to make clear that "sugar" in this context includes simple carbohydrates.

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  • [–] 19 points 9 months ago (13 children)

    I wonder if the US diabetic population is comparable to the Chinese diabetic population. Similar weight and eating habits? If not that could complicate things.

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  • [–] 40 points 9 months ago (11 children)

    Rate of diabetes in China “explosive”

    China has the world's largest diabetes population, with over 118 million adults (approx. 11–12% prevalence) living with the disease as of late 2024–2025, driven by rapid urbanization, obesity, and an aging population. The epidemic has shifted dramatically from less than 1% prevalence in 1980 to a major public health challenge, with type 2 diabetes accounting for over 90% of cases

    This is a consistent pattern in Chinese domestic politics. What a western nation would pick out as a profit center, the Chinese state addresses as a social cost. So the state plows a small fortune into cost-effective medical solutions, rather than squeezing the existing health care system out for therapeutic remedies that never resolve the root problem.

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  • [–] 9 points 9 months ago (6 children)

    This is a consistent pattern in Chinese domestic politics

    What are other examples?

    It should be noted that this treatment sounds likely to be very expensive, and also if someone doesn't change their lifestyle, the newly implanted functional cells are likely to become dysfunctional again over time, requiring another expensive cycle of treatment

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  • [–] 12 points 9 months ago (2 children)

    What are other examples?

    Environmental policy was a big one. China took a hard pivot in the '00s, cutting emissions, advancing alternative energy, reforesting deserts, rapidly advancing HSR, building enormous wild life refugees.

    Their insourcing of processors was another. Going from Taiwan's biggest customer to it's biggest competitor in a decade and change.

    Then there was the housing boom - remember "Chinese Ghost Towns"? All over the news in the early '10s. Now China has more homeowners than any other county on Earth with more than 90% of households owning at least one property.

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  • [–] 1 point 9 months ago* (1 child)

    i've never understood how anyone could think the "ghost towns" wouldn't obviously be filled shortly. One of the most significant facts about China is that they have a stupendously massive population, and consider Boston a quaint medium-sized town.

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  • [+] 3 points 9 months ago (3 children)
  • [–] 7 points 9 months ago (1 child)

    In the actual study, the subject had Type 2 diabetes, and the authors note that treating Type 1 will be much more difficult due to the immunology involved

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  • [–] 3 points 9 months ago

    Agreed, the article says all of this but it doesn't make a lot of sense. This is generally the mindset everyone has been using to treat type 1. Type 1 is about production, type 2 is about resistance. This treatment doesn't address resistance, it just makes more insulin. More insulin is not more better, and has consequences.

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  • [–] 2 points 9 months ago (3 children)

    This treatment is for type 1 (still 12 million cases).

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  • [–] 6 points 9 months ago

    I believe you may conflating type 1, and type 2. Type 1 does not have a causal relationship with food consumption. The article also might be conflating the two as it mentions curing type 2, but by using the methodology everyone has been looking into to treat the autoimmune issues of type 1s.

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  • [–] 5 points 9 months ago (4 children)

    Multiple types are autoimmune. Doesn't the body continue to attack the cells?

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  • [–] 5 points 9 months ago (3 children)

    This was one test in one patient. We didn't hear about the patients where this didn't work. Very shitty article.

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  • [–] 1 point 9 months ago (2 children)

    Well shit. At least I wasn't willing to get my hopes up.

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  • [–] 1 point 9 months ago (1 child)

    The concept is being trialed worldwide, but it will be too expensive for anyone

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  • [–] 172 points 9 months ago (6 children)

    They're getting new beautiful infrastructure and disease cures.

    We're bringing back measles, coal mining, and actively stupefying our kids for profit.

    USA! USA!

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  • [+] 7 points 9 months ago (4 children)
  • [–] 10 points 9 months ago

    The companies are still doing it, because it’s cheaper, and they rarely get in trouble. It’s a sign of Chinese capitalism, reckless disregard for harm done in the name of profit.

    80% of the sand used in their construction is now artificial... Because they stopped using unwashed sand.

    It took me less than 5 minutes to find this out with a simple search.

    'fun' read about able archer though.

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  • [–] 5 points 9 months ago (1 child)

    you're aware that americans just consider it completely normal to be able to punch a hole in a wall, right?

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    [–] 50 points 9 months ago (9 children)

    Is there a more reliable source than "HR News" ?

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  • [–] 25 points 9 months ago (3 children)
  • [–] 14 points 9 months ago (2 children)

    Yep, I tracked it back to that correspondence too. Key word there is “correspondence.” It’s not a complete research article, just a single report.

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  • [–] -4 points 9 months ago (2 children)
  • [–] 42 points 9 months ago (4 children)

    This "cure" was from 2024, per the South China Morning Post.

    In case anyone was thinking this was new.

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  • [–] 30 points 9 months ago (2 children)

    Any news on it since then? It wouldn't be the first time a scientific achievement out of China that embarrasses The West just fizzled out when no one was looking.

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  • [–] 1 point 9 months ago (1 child)

    Is it really an achievement if it fizzles out?

    A real groundbreaking achievement may travel slow, but it will stay steady since it actively improves lives. People will keep talking about it.

    Unlike, lets say, propaganda. That goes fast and fizzles out faster.

    We should be able to check if the amount of diabetes in China falls down rapidly.

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  • [–] 1 point 9 months ago

    It is if the results were falsified. Even it it worked somewhat, they're probably greatly over stating the effectiveness or ability to scale to a mass population.

    I remember years back, China solved world hunger by growing mushrooms in caves. I can't find anything on that anymore, but I still have a friend listing that accomplishment.

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  • [–] 48 points 9 months ago (2 children)

    Terrible hype article. This was one person. And, it's not unique, similar trials are taking place worldwide. But the US based development was all killed with the NIH cuts.

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  • [–] 4 points 9 months ago

    Sure thing, but I think that was the whole point of the article. It's not staying that America isn't enough technologically advanced to achieve that, but that nobody wants to do that because it would kill a huge industry 

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  • [–] 23 points 9 months ago

    I agree with most of the points regarding how how China does/would treat a diabetes cure in comparison to China, this post (it's not an article) is garbage. It's got no sources, just vaguely references a single case.

    It would be a better post if it didn't mention China at all and instead discussed how diabetes is approached under American capitalism.

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  • [–] 23 points 9 months ago* (1 child)

    People shouldn’t have to hope that Chinese scientists cure diabetes just so American companies can’t keep price gouging them. But here we are.

    here we are indeed

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  • [–] 23 points 9 months ago*

    It's a substack page, where they praise themselves for their "award winning journalism" so I would take this article with a massive grain of salt.

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  • [–] 83 points 9 months ago (7 children)

    I love how you call it Communist China when it's just as run-by-oligarchs as the US is. In fact they made an oligarch president for life.

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  • [–] 39 points 9 months ago (5 children)

    It's not communist, it's socialist with Chinese characteristics! (The characteristics are oligarchs)

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  • [–] 3 points 9 months ago* (4 children)

    It's not communist, it's socialist with Chinese characteristics! (The characteristics are oligarchs)

    Not for the 400m Chinese earning $40 USD a month.

    It's work till you die with no health care or social security.

    Not to mention the tens of millions of unregistered (citizenless) girls who are enslaved to work the world's biggest sex markets

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  • [–] 15 points 9 months ago (1 child)

    Ok, I'd really like to see a source for these claims because as far as I know the minimum salary is more than $200 everywhere in the country and the average is way higher. It might be work till you die, that I won't deny that, but they also do have social security and health care, to a degree that an US citizen would be jealous of.

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  • [–] 11 points 9 months ago

    my summary of china is that they have come to the genius conclusion that you actually have to feed your livestock if you want milk, which is something many other countries seem to have great difficulty comprehending.

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  • [–] 18 points 9 months ago (13 children)

    That's amazing! I wonder if the patients will have to get more insulin-producing cells transplanted every few years, or if this is a "one and done" type of deal?

    In any case, an autologous cell transplant every ≥3 years or so is a vast improvement over the current situation for type 2 diabetes

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  • [–] 18 points 9 months ago (2 children)

    US patients certainly will, if the cure is ever legal here.

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  • [+] 7 points 9 months ago (3 children)
  • [–] 3 points 9 months ago (6 children)

    IIRC the biologist that runs the YT channel Though Emporium did this some years ago regarding his lactose intolerance and he had to get more after some years because his body didn't naturally produce them

    But I hope this is different

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  • [–] 3 points 9 months ago

    lactose intolerance is a very very different thing from diabetes.
    Insulin is a fundamental part of keeping you alive, and if you fuck up the balance you can die which is why diabetes is such a big deal.

    Lactose intolerance is just the inability to digest a specific kind of sugar, which means bacteria in your digestive system can gorge themselves and give you an absurd amount of gas and other very unpleasant but ultimately not particularly dangerous consequences.

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  • [+] 3 points 9 months ago (4 children)
  • [–] 2 points 9 months ago (2 children)

    This is blatantly incorrect to a degree that i'd call it an outright lie, spending 30 seconds looking it up would show you that his video is literally titled "I Genetically Engineered MYSELF to Fix Lactose Intolerance".

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  • [+] 2 points 9 months ago* (2 children)
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    [–] 34 points 9 months ago (4 children)

    Ohhh nice... where is Communist China again... ?

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  • [–] 0 points 9 months ago (1 child)
  • [–] 2 points 9 months ago*

    Who said anything about how it looks?

    Shanghai is a global financial center, ranking third in Asia and eighth globally on the Global Financial Centres Index.[139] Shanghai is also a large hub of the Chinese and global technology industry and home to a large startup ecosystem. As of 2021, the city was ranked as the 2nd Fintech powerhouse in the world after New York City.[140]

    As of 2019, the Shanghai Stock Exchange had a market capitalization of US$4.02 trillion, making it the largest stock exchange in China and the fourth-largest stock exchange in the world.[141] In 2009, the trading volume of six key commodities—including rubber, copper, and zinc—on the Shanghai Futures Exchange all ranked first globally.[142] By the end of 2017, Shanghai had 1,491 financial institutions, of which 251 were foreign-invested.

    https://en.wikipedia.org/wiki/Shanghai

    Shanghai is about as communist as Wall Street. It should look nice, they certainly have the money for it.

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    [–] 15 points 9 months ago (3 children)

    wasn't the original inventor of insulin insistent that it remain cheap and readily available?

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  • [–] 14 points 9 months ago (1 child)

    Banting and Best sold the patent for $1. But they were Canadian.

    The cost of insulin has nothing to do with intellectual property.

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  • [–] 3 points 9 months ago

    They could have run a non-profit organization that leases out access to the patent, with conditions on pricing and availability. IMO, the pair thought that a for-profit health industry would do the right thing, and were betrayed by the rich bastards of society.

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  • [+] 10 points 9 months ago (1 child)
  • [–] 10 points 9 months ago
    [–] 7 points 9 months ago

    A book I was just reading talked about the pluripotent cells and using them for medical treatments. The author was talking to a US lab but then their work was cancelled due to funding cuts. Doesn't surprise me that China is taking up the slack.

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