The trick is to time the cocaine and crystal meth ingestion so that they peak at the same time that you orgasm, leading to an 80% * 300% * 1400% = 7460% 10700% dopamine increase.
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Sounds like a meth-cocaine orgasm is optimal then!
1780% 📈📈📈
The feeling you get when you peel the protective film off the door of a brand new refrigerator
And then replace it with a black garbage bag because it's a Samsung fridge
DMT springs to mind.
Having done all of these, DMT does not have the same kind of dopamine release. It is, however, the far most interesting of all of these. But definitely not something I’m ready to casually do at a party, unlike a couple bumps of fine Peruvian nasal fuel.
I'm with ya, I'm with ya. But smoking actual fine crystals in a glass pipe in the middle of the boreal summer in the morning hours may look suspec as fuc, but best god damned trip I've had in my life. And I've had about a gallon of LSD since I was a teen.
Pyrovalerones like MDPV and alpha-PVP are even stronger and more euphoric stimulants than meth. McAffee loved that stuff.
Heroin? I’ve read about people describing it as even better than an orgasm.
Have I been getting really bad coke?
Having had oodles of bad to mediocre coke in my days and then having 90+% pure (tested myself) I honestly think this graph is misleading, and coke is waaaaay higher.
The problem is, meth dumps your serotonin and feels good by itself, while coke requires you to be doing something that dumps your sweet brain chems to really feel good-good. I don’t know the science behind it but it’s been explained to me. Doing coke and sitting around watching a show is meh. Doing blow and playing a stimulating video game or doing a project that feels good or talking your partner’s ear off (and they yours in return) about ridiculous shit feels incredible.
But yeah. If you need to do a couple lines of coke to really feel it, it’s not good. If you’re getting zooted off a couple bumps, that’s the good stuff.
This person knows coke
Hahaha I had done it a few times during my rave phase but I was almost always disappointed. Like, you gotta do so much of it that it clogs your nose and it goes away so quickly! Then randomly an acquaintance of mine maaaany years later told me they dabbled (understatement) and I learned that almost all coke is complete garbage. A couple bumps had me zooted for like an hour. Remember kids, if it’s already a powder when it comes to you, it’s been stepped on. If you’re getting a shiny chunk that’s almost gummy-feeling, you’re in for a treat.
One of us!
It’s not even as expensive as people say it is. If it’s not shitty, ya don’t go through a ball in a night! My partner and I still occasionally dabble, and we maybe go through .1-.2 each for a couple hours of zoot.
The test kits are really cool, too. You break a glass ampule and shovel in a tiiiiny bit in. The shade of dark the chemicals turn tells you the purity. I’ve seen it turn a sludgy light-brown watery poo color a long time ago… and I’ve seen it turn black since then.
Once I found a good supply a ball would last over a week (unless I had some leaches). Before that i occasionally got stuff that did absolutely nothing.
Before the good supply I went home early one night without partying. Friends bought some stuff with fent in it. One friend ended up in the ER. They used paddles to get his heart started again.
Glad to say I no longer indulge.
Jesus! I’m so sorry your friend went through that, that’s awful! I’m very thankful for test strips now… it’s terrifying that something so opposite can just find its way into blow.
I’m glad you’re safe, and I hope your friend is okay now.
Good on you for no longer fuckin with it. My partner and I drink too much but otherwise are mainly sober from substances—we just have some random special days every couple months where we do something fancy and fun.
Crystal meth cured my autism
Source since op didn't provide it
Timestamp: 14:35
These drugs release endorphins not dopamine.
Dopamine is not a feel-good neurotransmitter.
It's widely misunderstood and misapplied.
Dopamine in the brain is actually more tied into motor control and function.
A loss of dopamine producing neurons causes Parkinson's. Interestingly, giving parkinson patients drugs to boost dopamine gives them schizophrenia like symptoms. Dopamine is not related to the reward feeling. Please stop pushing this narrative. It's probably one of the most annoying misunderstanding of modern neuroscience in the last few years.
Dopamine is implicated in part of the reward pathway but it is not the reward feeling.
Instead it is part of conditioning expectations for drug use related to behaviors that get the drug.
It's kind of complicated but again. It 100% is not a feel-good neurotransmitter.
It is not what makes you enjoy anything.
You are getting confused with endorphins.
And euphoric effects of drugs. Which are independent from dopamine.
Isn't dopamine causing the "yes I successfully did it" feeling too?
So. How much endorphins does meth give relative to other stuff on the chart?
That depends on theee things.
The dosage and the person's tolerance. And genetics.
Drugs that are ranked higher for drug addiction typically have strong fast effects and fast loss of the high.
But all drugs have addiction capabilities because of how tolerance in the body works. Tolerance, withdrawal, addiction. All part of the same process.
So back to addiction.
Cocaine. Immediate and intense high. But doesnt last that long. Same for the heroine.
Drugs like meth and adderall are basically exactly like cocaine in many ways except the high is actually more mild (per dose) and lasts longer.
Opiate medications can be seen as similar to heroine but. Last longer and not as strong.
Of course you can take larger doses of either of those two and get a stronger effect.
Even if you don't tho, people still get addicted to both of these more milder forms of cocaine and heroine. But just not at the same risk level.
And the risk declined drastically if taken at therapeutic levels (like following prescription drug directions).
Another thing you have to consider is genetics in brain receptors.
Some people's brain responds strongly in eurphoria to a drug while someone else's does not.
For example. Opiates. I personally do not get euphoria from opiates. I instead get a bad headache and extreme nausea. I had an injection of morphine about a year ago for a ER visit. Not only did it not help the pain at all, I had unpleasant effects from the drug. I was not high. But I was woozy. It was incredibly awful.
I actually told them not to give me optiates because I already knew I didn't tolerate them but that's what I get for going to a 1 star ER.
So how is it possible that a drug like an opiate wouldn't make me high or at the very least block the pain I was having ?
Genetics. My mother is the same. The part of other peoples brain that the opiate drugs bind to, will not accept the drug in my brain. Instead the drug is binding to some other receptors. Starting a cascade of signals that give me delirium, nausea, and a headache.
They are different enough to make a drug have a completely different effect in two animals of the same species.
It's things like that, that make designing drug therapies incredibly difficult.
So even when we try to give a basis run down of what drugs are highest risk, we can't say that's true for everyone.
There is zero chance I could become addicted to opiate based drugs. They literally are aversive to me.
It also means if I get injured and I'm in severe pain, there isn't much that can be done (so pretty big trade off. Here's hoping I don't get a painful terminal cancer).
So at present. Schedule 1 drugs have a specific definition. And that definition indicates a high risk of dependency.
You can read up more about how a drug qualifies for schedule 1. And schedule 2. I think that will help you understand the system better.
Orgasm is 80%, what's 100%?
Percentage of what?
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