There are standard tools available for this, I am using Brandwatch. I have excluded some known bots, but those are basically automods on Reddit.

We do control for other kinds of bot activity, for example we know bots post promos and deals on Twitter and Reddit for affiliate marketing reasons, and we exclude them using hashtags known to be used for this. But other than that if you are referring to misinformation bots, in my experience that is a much smaller problem. I had run an analysis on r/conservative subreddit when the Yandex data center news broke and it did not not have visible impact on posting activity on that sub.