Block everyone! Block every instance! Block me! Block yourself!

Or maybe... just spend some time using the platform until you start to get a feel for the vibe. If you can bear to listen to opinions that don't already align with your own, you'll probably find that most people are pretty chill and discussions are mostly pretty civil. Disagreement is not the same thing as hostility or trolling. I've never blocked anything on this platform and I still find it to be miles better than reddit in terms of vibes. Rather than preemptively curating your feed based on whatever someone else's idea of bad content is, you can form your own opinions. Block if you want, but you can also just... not engage.