In my vehicle I have a safe that's inside a separate steel box that's bolted through the floor in a manner that stealing the safe itself would require removing the fuel tank. So when I'm out and about somewhere I can't or shouldn't carry my gun is securely stored. Im confident in that safe because the vehicle was stolen from the previous owner and the car thieves were unable to access the safe prior to ditching it.

At home, it's always nearby. I live alone, and if company is coming over I can put it in the safe with the long guns easily enough. When I leave the house it comes, with me and gets put in the car safe when I'm in the office.