186
AI finds signs of pancreatic cancer before tumors develop (www.nbcnews.com)
submitted 6 months ago by to c/technology@lemmy.world
32 comments fedilink hide all child comments
you are viewing a single comment's thread
view the rest of the comments
[+] -15 points 6 months ago* (last edited 3 months ago) (7 children)
[deleted]
  • permalink
  • fedilink
  • source
  • parent
  • hideshow 7 child comments
    •
  • [–] 28 points 6 months ago* (4 children)

    False positives are at least as dangerous as false negatives and AI solutions like this have massive problems with over diagnosing.

    Absolutely 100% wrong.

    In pancreatic ductal adenocarcinoma, a false positive means a follow-up scan. A false negative means death, the 5-year survival is near zero once it's caught late, but exceeds 80% when caught early.

    In the study, the radiologists' lower false positive rate is achieved by missing 78% of cancers. That's not a safer trade-off, it's just a different way to fail. "Overdiagnosis" also requires a disease that might not have harmed the patient, PDA doesn't have a harmless form. Every missed case is a lost life while every false positive is an extra doctor's appointment.

    This system detects twice as many cancers and was flagging them, on average, 675 days (nearly 2 years!) before clinical detection.

  • permalink
  • fedilink
  • source
  • parent
  • hideshow 4 child comments
    •
  • [+] -21 points 6 months ago* (last edited 3 months ago) (4 children)
    [deleted]
  • permalink
  • fedilink
  • source
  • parent
  • hideshow 4 child comments
    •
  • [–] 18 points 6 months ago

    If I'm wrong, then feel free to support your position with evidence or an argument showing that my statement was specious.

    I linked the, peer-reviewed, paper which contains the data that supports my statements on the topic.

    You've made two conclusory statements and immediately resorted to insulting comments when challenged.

    There is not a single aggressive pancreatic cancer where a false negative is more dangerous than a false positive.

    Percutaneous biopsy has a mortality rate of approximately 0.2% even relatively non-malignant pancreatic cancers (say Solid pseudopapillary neoplasm) have 10-year survival rates in adults of around 88% and that number is from cases which received surgical intervention and chemotherapy something that would not happen with a false negative.

    So even in the worst case, the false negative multiple times more deadly. A false positives' most likely outcome is pancreatitis from the biopsy procedure.

  • permalink
  • fedilink
  • source
  • parent
    • load more comments (-1 replies)