False positives are at least as dangerous as false negatives and AI solutions like this have massive problems with over diagnosing.
Absolutely 100% wrong.
In pancreatic ductal adenocarcinoma, a false positive means a follow-up scan. A false negative means death, the 5-year survival is near zero once it's caught late, but exceeds 80% when caught early.
In the study, the radiologists' lower false positive rate is achieved by missing 78% of cancers. That's not a safer trade-off, it's just a different way to fail. "Overdiagnosis" also requires a disease that might not have harmed the patient, PDA doesn't have a harmless form. Every missed case is a lost life while every false positive is an extra doctor's appointment.
This system detects twice as many cancers and was flagging them, on average, 675 days (nearly 2 years!) before clinical detection.