Just Shoot Me.

I randomly came across Dirk Gently's Holistic Detective Agency on Hulu and it quickly became one of my all time favorites. Super interesting characters.

Better Off Ted

The workplace comedy about Veridian Dynamics, the company that can make anything, whether it's a good idea or not.

It was on a major network, but the timeslot kept abruptly changing and the final two episodes were preempted by a live sports event, and never even aired in the US.

Veronica: Ted, we need a mouse that can withstand temperatures of up to 300(?) degrees.

Ted: Live mouse or computer mouse?

Veronica: ....I'll get back to you.

An attempt at creating an artificial meat:

Jerome: It tastes familiar...

Ted: Beef?

Jerome: No...

Linda: Chicken? We’ll take chicken.

Jerome: [Shakes head.]

Ted: What does it taste like?

Jerome: Despair.

Ted: Is it possible it just needs salt?

Pantheon.

Pantheon.

Seriously, watch Pantheon if you haven’t already. Its screwed up release/licensing (died on the vine on some AMC streaming service) is a crime against humanity.

I literally can't say anything else about it without spoiling it, other than it's some of the best sci-fi ever, and its pacing is fast.

Travelers is quite good and I don't see it being mentioned as much online. Has a lot of ex Stargate extras.

Person of Interest was a show that started episodic and evolved into an incredibly thrilling epic. Fuck the main actor though.

Better Off Ted is one of the funniest shows I've ever seen and it pisses me off to no end that it flopped

Not sure how "lesser known" it is, but I can't recommend Final Space enough

Galavant! The medieval, comedy musical!

Detectorists was very well done. It’s a brief 20 episodes over three seasons and a couple specials, and it’s buttoned up so well at the end. Highly recommend!

The Patriot on prime is the best show nobody's watched. It doesn't have a single bad episode, the plot, dialogue, acting and production values are outstanding. It was cancelled after 2 seasons but is still really satisfying. Absolutely love it!

The Thick of It, for my unstimulated, laugh-track hating siblings out there. It's 'better' than The Office (both versions), better than Seinfeld (is this even a relevant mention nowadays?), and just under Sunny because Sunny ran for at least 12 extremely solid seasons while The Thick of It is a 3 season show. Strong recommendation for anyone who can process information efficiently!

Lodge 49, Lodge 49, Lodge 49! Probably one of my top 5 shows in the last decade. Every single review I have ever seen both professional and rando cannot stop raving about it, but still nobody watched it. I think mostly because it's kind of hard to describe and doesn't fit cleanly into any particular box.

Only downside is that it suffered a pretty sudden cancellation after season 2 was shot, so there is no satisfying resolution. Although Wyatt Russell has said repeatedly that he'd drop absolutely any project for a chance to revive it

Flashforward from 2009. It’s based on a book which is also awesome, but the show really nailed it.

The cast is totally stacked with amazing talent, and the plot/concept is really unique and well-executed. Highly recommend.

Turn was a good series. It’s about spies during the American Revolution

I’m not sure if it went under the radar or if I just got into it late, but Fringe is a great show that has a lot of interesting twists. I haven’t watched it in a while and I’m planning a rewatch soon.

Carnivale. Too bad it didn't get a proper ending.

Better off Ted. Funny stuff.

Terriers.

A Touch of Cloth.

A parody of British police procedurals in the vein of Police Squad/Naked Gun. One of the creators is Charlie Brooker, who also created Black Mirror.

(The title is a pun on the title of a British police procedural called "A Touch of Frost" and the euphemism "touching cloth".)

Future Man

I quite liked Continuum, but it never seemed to enter the zeitgeist. It is still one of my favorite time travel series'.

Younger people should watch Taxi. It didn't fly under the radar but it's old enough to be fresh even if you've seen it. My favorite new discovery for sure

Banshee was very good. Some other series that didn't seem to be "big" but I enjoyed are: Hell On Wheels, Mr. Inbetween, Preacher, SAS Rogue Heroes, Tacoma FD and Warrior

Best show I’ve seen in the past couple years is a single season mini series called “The Investigation” a Danish series about a true murder that occcurre and the investigation into it following. Really well done.

Remember WENN. A performance driven comedy that takes place almost completely at a radio station in the 40s. Has a very theater play feel.

Clever dialog and great acting.

Kipo and the Age of Wonderbeasts. Western animation series on Netflix. Coming of Age story, post-apocalyptic sapient mutant animals, representation that's neither perfunctory nor performative, inclusiveness triumphing over intolerance, and it occasionally involves a little bit of Kaiju combat. All that and they got a proper ending.

The Magicians

Off the top of my head, Oz and The Americans are under-appreciated.

https://en.m.wikipedia.org/wiki/N%C3%A6turvaktin and its sequel series are really good, if we want to go proper-obscure.

Wise Guy and Crime Story.

Grimm is a really good show that I'd never heard of before until somone mentioned it on a thread like this one and I gave it a chance.

BBC’s “Survivors”. The 1970s original, not the later remake. About the people left over after a pandemic.

1971 “The Guardians” also from BBC. About fascism in a near future UK.

“Thriller” another British show from 1974. It’s an anthology series centered around a mystery/suspense/horror story each week. The Helen Mirren and Bob Hoskins episodes are particularly good.

If you are a British millennial then you've probably heard of BrassEye, but everyone else should seek it out. Absolutely hilarious.

Brockmire had some success, but I've never mentioned it to anyone who's actually watched it. The comedy is outrageous, and the characters are awful, but you fall in love with them. It's so good.

The Whitest Kids You Know - Great shortlived sketch comedy show.

As a few other have mentioned Mr Inbetween is the greatest show that America didn't watch.

I don't know quite how obscure it is because of how it ended up, but Summer Camp Island.

It's a 6 season Cartoon Network cartoon about a group of kids who attend a summer camp on a magical island with 3 teenage witch camp counselors. First maybe season or 3 the show is mostly episodic and can be watched in any order after the first establishes some things.

Later seasons they really start having more lore and push more story driven narratives ( and even dividing the season into little character focused mini-arcs for one season ) into the picture. Season 6 definitely felt a little rushed ( probably because cartoon network/hbo just wanted the series finished so they could quickly shove it out and then kill it for tax purposes ), but it has some pretty amazing moments and themes later on. For pretty much as much of the series as I can remember, the show doesn't have a bunch of "lol random!" style comedy, so you shouldn't have to worry about that.

One of my biggest gripes is that there's a later season episode I absolutely cannot watch as someone with arachnophobia because it involves one of the main characters and a talking spider. Other than that, it's how the pacing can feel a little rushed towards the end of season 6 ( which I, again, attribute the most likely cause being corporate telling the people behind it that they don't get a season 7 so they better wrap things up as fast as possible ).

The Purge
You, Me & the Apocalypse

Star Trek Prodigy!

Slings and Arrows

American Vandal has two seasons on Netflix. It’s a straight faced investigative series of some high school pranks writ large. It’s fucking hilarious.

For fantasy buffs, check out Sam Raimi's 'Legend of the Seeker' 2008-2010 series, one of my favorites.