High-profile studies reporting the presence of microplastics throughout the human body have been thrown into doubt by scientists who say the discoveries are probably the result of contamination and false positives. One chemist called the concerns “a bombshell”.

Studies claiming to have revealed micro and nanoplastics in the brain, testes, placentas, arteries and elsewhere were reported by media across the world, including the Guardian. There is no doubt that plastic pollution of the natural world is ubiquitous, and present in the food and drink we consume and the air we breathe. But the health damage potentially caused by microplastics and the chemicals they contain is unclear, and an explosion of research has taken off in this area in recent years.

However, micro- and nanoplastic particles are tiny and at the limit of today’s analytical techniques, especially in human tissue. There is no suggestion of malpractice, but researchers told the Guardian of their concern that the race to publish results, in some cases by groups with limited analytical expertise, has led to rushed results and routine scientific checks sometimes being overlooked.

The Guardian has identified seven studies that have been challenged by researchers publishing criticism in the respective journals, while a recent analysis listed 18 studies that it said had not considered that some human tissue can produce measurements easily confused with the signal given by common plastics.

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[–] 26 points 10 months ago (1 child)

Petroleum industry-sponsored criticism, or is it legit?

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  • [–] 13 points 10 months ago

    My understanding is it's legit. The original studies included a Margin of error which was not included in the headlines, shockingly. This new figure is within those margins.

    The problem is with the testing method used to identify the plastic, it also detects a bunch of other stuff that's supposed to be there.

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  • [–] 4 points 10 months ago (7 children)

    That was my impression for a long time. Microplastic everywhere, all at once, suddenly? Or just plastic from pipettes, probe containers, plastic tubes in test equipment?

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  • [–] 9 points 10 months ago (4 children)

    It seems it’s more like cells can naturally produce substances that are detected as microplastics.

    Also things like shredding from pipettes would almost certainly have been detected earlier given how ubiquitous they are in research.

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  • [–] 1 point 10 months ago (3 children)

    I would not consider it unlikely that those one-use items like they are used in labs shred way more particles than those that have been used several times with cleaning cycles in between.

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  • [–] 3 points 10 months ago (2 children)

    I’d be curious what the values are. There’s a lot of variation based on how the plastic is formed and treated. E.g. abrasion causes a lot of shedding. It’s possible that heading and washing can also cause degradation.

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  • [–] 1 point 9 months ago (1 child)

    Those values are probably the key points. I know from experience that they shed less and less over time, but I have no means to put numbers to that.

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  • [–] 1 point 9 months ago

    from what I've read, most of the particles of ultra-fine plastics are dryer lint, which really are sooo damn small, that they can get into everything.

    It's sorta like those researchers who went into a city, to get pollen-samples from the air, & ..couldn't find any, among all the tire-particles their filters caught..

    IF there's an absolutely-pervasive population of particles, then .. they could actually be expected to get into everything..

    now I even remember some arctic researchers, who woke-up to black snow: coal-soot from China ( pollen identified where it was from )

    The finest particles travel

    _ /\ _

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    7 comments in c/science@lemmy.world view that post
    [–] 21 points 10 months ago

    So, just science being science then? Disagreements have always been a part of science, and always will be. The only important factor is how they are handled. Think a study is flawed? Repeat it, and change the flaws to see if the results differ significantly. But openly discrediting any evidence (for or against a case) without testing is as unscientific as it gets. I believe the person at the end also has a point: yeah, we don't know if microplastics are as bad as they say, but better safe than sorry.

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  • [–] 8 points 10 months ago (3 children)

    I don't get the downvotes. The article explains that many researchers pointed out methodological issues in the tests measuring microplastics and the implausibility of some results. An the criticism was made writing letters to the respective journals that published the results, i.e. at the highest level, even some authors admitted the possibility of mistakes in the results. Sounds good news to me and honestly having microplastics in the brain equivalent to a credit card was hard to believe.

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  • [–] 2 points 9 months ago

    And this is why the current system (the tabloidisation) of publishing is a danger to science itself, because people might lose trust in it.

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  • [–] 1 point 10 months ago
    2 comments in c/science@slrpnk.net view that post
    [–] [S] 9 points 9 months ago* (1 child)

    A longer excerpt that sheds light on the measurement problems which research into microplastics is facing.

    A key way of measuring the mass of MNPs in a sample is, perhaps counterintuitively, vaporising it, then capturing the fumes. But this method, dubbed Py-GC-MS, has come under particular criticism. “[It] is not currently a suitable technique for identifying polyethylene or PVC due to persistent interferences,” concluded a January 2025 study led by Dr Cassandra Rauert, an environmental chemist at the University of Queensland in Australia.

    “I do think it is a problem in the entire field,” Rauert told the Guardian. “I think a lot of the concentrations [of MNPs] that are being reported are completely unrealistic.”

    “This isn’t a dig at [other scientists],” she added. “They use these techniques because we haven’t got anything better available to us. But a lot of studies that we’ve seen coming out use the technique without really fully understanding the data that it’s giving you.” She said the failure to employ normal quality control checks was “a bit crazy”.

    Py-GC-MS begins by pyrolysing the sample – heating it until it vaporises. The fumes are then passed through the tubes of a gas chromatograph, which separates smaller molecules from large ones. Last, a mass spectrometer uses the weights of different molecules to identify them.

    The problem is that some small molecules in the fumes derived from polyethylene and PVC can also be produced from fats in human tissue. Human samples are “digested” with chemicals to remove tissue before analysis, but if some remains the result can be false positives for MNPs. Rauert’s paper lists 18 studies that did not include consideration of the risk of such false positives.

    I can only conclude that a better measurement method is needed. Either the vaporization of samples or the chemical digestion will have to be replaced - but what that method will be, I can't guess.

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