cross-posted from: https://discuss.online/post/48201538

http://www.smbc-comics.com/comic/friendship-2

Alt textLater it turns out to be a gay bar, and things go better than expected.

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[–] 5 points 1 day ago (4 children)

Your paracetamol is no better, just hurts a different organ.

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  • [–] 3 points 1 day ago (3 children)

    Where have I mentioned paracetamol?❓❓

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  • [–] 2 points 17 hours ago (2 children)

    What OTC do you use for minor aches and pains? Naproxen is also bad for your liver.

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  • [–] 1 point 4 hours ago (1 child)

    Aspirin, Voltaren, and not being a pussy.

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  • [–] 2 points 2 hours ago

    Main Reasons Doctors Avoid Diclofenac

    Cardiovascular Risks: Diclofenac increases the risk of serious heart attacks, strokes, heart failure, and blood clots at a rate comparable to specialized COX-2 inhibitors (like rofecoxib). Studies show these cardiovascular risks can begin within just 30 days of starting the medication, even at low doses.

    The People's Pharmacy

    +4

    Gastrointestinal Complications: Like other NSAIDs, it blocks protective prostaglandins in the stomach, which can lead to severe ulcers and a 4.5-fold higher risk of gastrointestinal bleeding compared to non-users.

    Pulse Today

    +1

    Kidney and Liver Strain: It can reduce blood flow to the kidneys—causing acute kidney injury or worsening blood pressure—and has been linked to drug-induced liver damage.

    Safer Alternatives Exist: Other nonselective NSAIDs like naproxen or low-dose ibuprofen generally offer a more favorable cardiovascular and safety profile for long-term use. Guidance from organizations like the GOV.UK Drug Safety Update explicitly contraindicates systemic diclofenac for patients with established ischemic heart disease, peripheral arterial disease, or heart failure.

    nhs.uk

    +1

    Ok, whatever man.

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