I use synctging for other stuff, so for me it was a bit of a nobrainer to use it for obsidian too. I have run into some issues. Notably with trash. It will very often try, and fail, to sync trashed files. I have to put a lot of stuff in the ignore field for all my files to make it stop spitting out errors all the time. I think the best part of it though is that it works so smoothly the rest of the time. I almost never even need to think about it nowadays, now that I've got it all setup.
Just be aware that there are some characters that obsidian allows in file and folder names that cause syncthing to throw a fit. Like question marks. Oh god why do question marks cause so many issues in syncthing its awful.