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Vyvanse makes the line go up (piefed.cdn.blahaj.zone)
submitted 6 months ago by to c/adhd@lemmy.dbzer0.com
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A skeleton squats a barbell behind text that reads “my body is a machine that turns lisdexamphetamine into shareholder value “
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[–] 2 points 6 months ago (12 children)

damn, did it worked for you? onwas at 40mg and didn't notice any difference, how much y'all take?

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  • [–] 5 points 6 months ago (2 children)

    30mg. I sometimes have worse anxiety when it occurs, but my memory now works and I can engage in tasks for 12 hours in a row.

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  • [–] [S] 4 points 6 months ago (4 children)

    I take 30mg in the mornings, it works pretty well for me. I took 70mg once and had an absolutely miserable time, it was way too much

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  • [–] 1 point 6 months ago (3 children)

    Yall taking the og right? The generic is absolutely fucking garbage and doesn't work for shit.

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  • [–] 3 points 6 months ago (2 children)

    I don't think it's quite like that, I think it's more that an important part of these drugs is the release mechanism - and any two given brands will work differently for a given person.

    I take long release methylphenidate (Ritalin/Concerta being the most known brands). I started with Medikinet because that's the main recommendation from my healthcare provider. It turned out it releases most of the dosage in the short term and at 40mg doses I constantly felt like I was at an airport with my boarding gate closing in seconds.

    Moved to Meflynate, which is also methylphenidate hydrochloride, and now I'm a happy bunny.

    My point being - it's not that generics are bad necessarily, it's more like, only a certain brand(s) will work for you. Whether for you that's the more expensive or cheaper one, it's a bit of a lottery really.

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  • [–] 3 points 6 months ago

    Lisdexafetamine is somewhat unique because the slow release mechanism is more or less inherent to the actual drug itself. That is, the fact that lisdexamfetamine is a prodrug that needs to be processed into dextroamphetamine (the actual stimulant) is the slow release mechanism itself.

    Methylphenidate is different because the chemical itself is the stimulant, so pharmaceutical companies need to come up with ways to physically release it slowly, e.g. via mini capsules that dissolve slowly.

    Unfortunately every brand and formulation kind of does their own thing in order to differentiate themselves from generics.

    IIRC Concerta was the most "advanced" in the sense that they formulated a special double release system where each dose also dissolved slowly. Ritalin LA is much jankier because it basically just released a second or third dose all once later on.

    You can search "name of drug" + pharmacokinetics to get more graphs, which in combination with keeping a mood diary can help in nailing down hat works for you.

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  • [–] 1 point 6 months ago

    Yeah that's the thing it's all about the time release. Correct me if I'm wrong but vyvance big thing is that it.... fuck I forgot it the most of it but it slowly release through the liver because of a extra molecule on the drug. This makes it that your body only sucks it up as needed. When blood levels drop. So allegedly its damn hard to overdose on vyvance. The larger doses are only for how long of a day last for. 40mg 8hrs 60mg 10hrs etc.

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  • [–] 3 points 6 months ago (2 children)

    I'm on 70mg of Elvanse (same stuff) and I've finally started to feel it but its subtle. The appetite suppression kicked in down at 30mg but the focus and mental shift (feeling good and not resentful at completing tasks and things which seemed impossible to tackle don't look as daunting which helps with procrastination) really didnt happen until I hit 70mg.

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  • [–] 2 points 6 months ago (1 child)

    I'll try. just once, given that it gives me high blood pressure. my max dose was 40mg, and I got frustrates and began thinking they gave me placebos or some building.

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  • [–] 2 points 6 months ago

    In my experience it requires a bit of mental effort to go along with it rather than waiting for it to have an obvious effect. Like with painkillers or antidepressants you can feel it affecting you without needing anything on your part. Elvanse for me has been more like, I still need to make a huge effort for things like getting out of bed or to not procrastinate but that "barrier" is lower and once you start you can just stick to the task a lot easier. So its more like an assistance or booster that doesn't do much by itself rather than an obvious "cure" of symptoms and behaviour.

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