I can think of lots of series that I don't like, just because I'm not into the genre. I think that everyone has genres that they don't like.

I think a more-interesting question is about popular series that I don't like within a genre that I do like.

I didn't like Frostpunk, despite liking city-builders. Felt like the decisions were largely mechanical, didn't involve a lot of analysis and tweaking levers.

I didn't like Sudden Strike 4, despite liking lots of real time tactics games, like Close Combat. It felt really simplified.

I didn't like Pacific Drive, despite liking survival games. It has time limits, and I often dislike time limits in games.

I didn't like Outer Wilds, despite liking a lot of space games. Didn't like the cartoony style, the low-tech vibe, felt like it wasn't respectful of player time.

I didn't like Elden Ring, though I like a number of swords and sorcery games. Just felt simple, repetitive and uninteresting.

EDIT: A couple of honorable mentions that I don't hate, but which were disappointing:

Borderlands. The gunplay can be all right, and the flow of new guns and having to adapt to them is interesting. But every Borderlands game I play, the always-respawning enemies are a turnoff. Feels like the world is immutable. Also don't like the mindless farming of every container with glowing green dots. And for a combat-oriented game, it doesn't make me mix up my tactics much based on whatever I'm facing. While I finish the game, I always wind up feeling like I'm not having nearly as much fun as I should be having.

Choice of Games. I like text-based games, but a lot of games published by this company, even otherwise well-written ones, have adopted a convention of making one win by playing consistently to certain characteristics of a character, so one tries to just figure out at every choice what option will maximize that characteristic. That's extremely uninteresting gameplay, even if the story is nice and the text well-written. I feel like the same authors would have done better just writing choose-your-own-adventure type games if they weren't focused on the stats. I also really dislike the lack of an undo, to the point that I've put some work into a Choicescript-to-Sugarcube converter.