My first full Factorio playthrough was a Lazy Bastard run. The game is a lot more chill when turning off biter expansions & turning up trees slightly in the map gen.

Granted I think I racked up like 200hrs in that run, largely because I could leave the game running in the background whilst going off to study or do other stuff. Once you're past the intial stage & have a mall set up, hand-crafting really doesn't matter much.

There is no spoon was alright as a goal, but it also ends up being a definitive end to that playthrough (which, arguably, can be both good and bad).