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Cancer jab can eradicate entire tumours in patients, trial shows (www.theguardian.com)
submitted 5 months ago by to c/science@lemmy.world
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Doctors have hailed “unprecedented” trial results that show a triple-action cancer jab can eradicate entire tumours in patients.

In an international trial spanning 11 countries, the injection was offered to patients whose cancer had spread or come back and whose disease had failed to respond to other treatments.

The jab, called amivantamab, shrank the tumours of more than a third of patients, with dramatic changes seen within weeks. In 15 of them, doctors found the drug had melted away their tumours altogether.

Kevin Harrington, professor in biological cancer therapies at the Institute of Cancer Research, London (ICR), said: “These are unprecedentedly strong responses in patients whose disease has become resistant to both chemotherapy and immunotherapy.

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[–] [S] 31 points 5 months ago (1 child)

Some wild, but positive, news this morning.

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    • [–] 21 points 5 months ago

    Oh this sounds like really good news. I could use some good news for once.

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    [–] 39 points 5 months ago (4 children)

    It'll cost $55000 in the US and $5 everywhere else

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  • [–] 18 points 5 months ago (2 children)

    You have to be joking right?? It'll cost literally millions of dollars per jab here in the ol' divided states of america.

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    • [–] 11 points 5 months ago* (last edited 5 months ago)

    I wonder how long it'll be before this becomes the primary treatment. I sure know that I'd prefer this over the other options even if the odd were slightly worse

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    [–] 9 points 5 months ago

    Amivantamab (monoclonal antibody) is mentioned at least twice in the congress materials below.

    Congress Materials – American Society of Clinical Oncology (ASCO 2026) https://www.jnjmedicalconnect.com/therapeutic-areas/oncology/congress/asco-2026

    https://www.cancernetwork.com/view/amivantamab-regimen-boosts-survival-in-egfr-nsclc-subtype

    https://www.ajmc.com/view/amivantamab-plus-folfox-folfiri-demonstrates-strong-durable-activity-in-mcrc

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    [–] 6 points 5 months ago

    Very promising, this is great news!

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    [–] 10 points 5 months ago (1 child)

    I can't wait to never hear about this ever again

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  • [–] 2 points 5 months ago*

    It does seem like we see these stories, and then never hear about them again. On the other hand, we get assaulted by pharmaceutical ads constantly, so they seem to be coming up with plenty of new stuff.

    They came up with all these new fat drugs, and just a few years ago I would have scoffed that anything like that would ever exist.

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    • [–] 5 points 5 months ago (2 children)

    I just saw a story on a new drug that works wonders on pancreatic cancer, which is particularly deadly, doubling life expectancies, and may work on other cancers as well. Hopefully, they'll start combining these drugs, and we'll see a huge improvement in outcomes.

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    • [–] 22 points 5 months ago (5 children)

    It is bizarre to see a presumably serious article repeatedly use the term "jab" for a medical procedure. It's an antivaxxer trope and really doesn't belong anywhere near a scientific discussion

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  • [–] 30 points 5 months ago* (last edited 5 months ago) (1 child)

    It's an antivaxxer trope

    In the US, sure, but in the UK, it's been the main "jocular yet not unprofessional" term for decades, with neither negative nor positive connotations.

    Just like how the majority of their biggest tabloid headlines are puns. British journalists are just built different for better and for worse 🤷🏻

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  • [–] 3 points 5 months ago* (last edited 5 months ago) (1 child)

    Nah, all of us who were very happy to get the vaccine proudly said "we got the jab"

    Maybe antivaxxers then tried to claim it, but the first round of folks prioritized for the vaccine (eg healthcare workers) used it in a positive way first

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    • [–] 3 points 5 months ago

    Is that the one the cubans developed?

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