Will and Grace. Late 90s but still counts

Kids in the Hall

I just finished all seasons of Party of Five. The final season had a prominent, supporting gay character. But all through the show, they were surprisingly inclusive in general, in their topic matter.

Ellen, My So Called Life, Designing Women, Friends

Edit: Just noticed "best". Sorry. These might be debatable for that.

Willow Rosenberg on Buffy The Vampire Slayer.