From the actual study[0]

Human cerebral microvascular endothelial cells (hCMECs) were cultured and treated with 6 mM erythritol, equivalent to a typical amount of erythritol (30 g) in an artificially sweetened beverage, for 3 h.

Am I reading this right? They basically soaked brain cells in diet soda for three hours?

[0] https://journals.physiology.org/doi/full/10.1152/japplphysiol.00276.2025

Relevant as ever..

“…The researchers did not yet test this in people. They went straight to the cells that line your brain’s blood vessels…”

I was expecting yet another aspartame-bashing article, but it's an erythritol-bashing one this time.

Look, it's really simple: all those sweeteners have been in widespread use for a long time. Wanna know if they're harmful? Do some stats correlating release dates in several countries and occurrence of this-or-that disease and death records. If you can't find a statistically-significant correlation, well... it doesn't prove the stuff is harmless, but chances are it is.

That's assuming there aren't already a kajillion inconclusive studies on the particular molecule you're interested in, as with aspartame.

Regardless of the methodology used for this study, I’ve switched to pure stevia now. I hate that a lot of stevia products actually use erythritol and just list it in small font.

Whatever it does, it makes me feel like shit, so I avoid it.