Male, 40, 250 pounds (120kg) lifting seriously for 10 months. 💪

According to Jeff Nippard, 10 or more sets per week per muscle group is optimal for hypertrophy. Problem is, however, fatigue is multidimensional—local/peripheral (muscle metabolites, calcium handling, connective tissue), central/systemic (CNS, immune, endocrine), axial (spine/hips), and psychological. To add insult to injury, a certain type of prescription medication I take masks fatigue and boosts mesolimbic neurotransmitters (dopamine, norepinephrine) further exacerbating the problem.

As a result, I struggle to do more than 10 working sets per day, even when I split my daily volume into a morning session and afternoon session with 3-5 minute rests between sets. If I do more than this, I begin to fall behind in my personal life. (apparently "executive function" is one of the first victims of collateral damage for training too hard)

I take ice baths regularly in 6C water. I pride myself on mental toughness so it's not simply a matter of being lazy or cowardice. I'm also totally fine with doing 10 working sets per day because I've made more progress than I ever thought possible and if 10 working sets per day is my limit, I'm fine with that. I'm not complaining, just asking out of curiosity in case others here have gone through this and figured out a solution to this mildly annoying problem.

TL;DR: Is "lowering the systemic cost per set" the only viable solution for a lackluster systemic fatigue ceiling? (i.e. incorporating more "greasing the groove" style training that utilizes a high percentage of 1RM coupled with low RPE and high RIR)

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[–] 4 points 20 hours ago* (last edited 18 hours ago) (3 children)

This isn't a direct answer, and I'm not an expert. I would say that increasing your total weekly volume should be one of the last things you should do to increase hypertrophy. Volume itself has pretty drastic diminishing returns, and early on is a good way to push, but it falls off fast for the effort involved. Sets 5-10 do a lot more for you than 11-20 (edited reps-sets).

I would focus on training sufficiently close to failure, them increase your frequency. If you can hit the same muscle 3x a week instead of 1 or 2x, it's going to be a much bigger difference than slamming more reps onto the same workouts.

With that being said, for increasing lifting stamina, I wanted to do it, I would make sure your nutrition is on target and get good rest, then just slowly ramp up the volume and see what you can handle and adjust accordingly.

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  • [–] [S] 2 points 18 hours ago* (2 children)

    I would say that increasing your total weekly volume should be one of the last things you should do to increase hypertrophy.

    According to Jeff Nippard, you must do a minimum of 2 hard sets per week per muscle group to maintain muscle mass. (or 1 near-death set where you collapse to the floor immediately after your final rep, Mike-Mentzer style exertion)

    I only hit 10 weekly working sets for 1 muscle group (front delts). I do 2 working sets of lower body weekly. 6-8 hard sets per week of side delts. 4 hard sets per week of triceps/biceps. 2 hard sets of chest. No weekly minimum for calves, quadriceps, trapezius, back, lats, etc... (I just only care about front delts so everything else is deprioritized until I've dropped 50 pounds (25kg) of excess bodyfat very slowly)

    My weekly volume is pathetically low, especially now that I'm in a very modest calorie deficit of ~400 calories or 3 pounds per month. I should have mentioned in OP that I can only do 10 working sets per day when I'm not in a calorie deficit -- but my question is still the same as I will still want to know how to fix this in a year when my diet is over.

    Reps 5-10 do a lot more for you than 11-20

    Doesn't this go against the idea of "effective reps" for hypertrophy? i.e. the last 5 reps before failure are the only reps which matter? (as explained in this Jeff Nippard video below):

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  • [–] 3 points 18 hours ago

    From experience, it is quite difficult to add significant volume in a deficit. The more extreme, the harder it is, especially as you get leaner and leaner. I could do 20 sets per week starting out at 220 lbs, but as I got closer to 15% and, I had to drop back to just 8-10 hard sets per week per muscle.

    It sounds like you're doing solid though. I think it's worth just focusing on sustainability during the cut to get to your lean-ness goal, then really hammer down when you switch to maintenance or a clean bulk. I think you'll be surprised how much more you'll be able to handle with you're not in a deficit.

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  • [–] 3 points 18 hours ago

    That last bit, I meant sets, not reps. So fair catch. The first few sets do the majority of the growth stimulus compared to the later sets. Doing 1-2 hard sets a week gets you like 70℅ of the potential gains (I don't remember the exact number) and as you add sets, you get asymptotically closer to 100% of potential gains.

    I'll edit the comment for clarity.

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  • [–] 2 points 13 hours ago (1 child)

    First - everyone’s capacity is different; science discovers averages. There’s freaks who can do 20 sets and people who can do 5.

    Over time you may be able to increase your tolerance slightly but recovery is ultimately a limited resource. Sleep, diet, and reduced stress outside of the gym are the only three things that I’m aware of that will help. When I had a job that basically was 2hrs a day, my diet was clocked in, and i was sleeping super regularly, I could do a lot more in the gym than I am now. I’m repeating a cycle from several years ago and I think my fatigue is more than just age.

    The other area you can improve recovery and overall capacity with is performance enhancing drugs. That’s something I don’t really know too much about, but that’s the way I’ve heard it described - you heal faster, stronger.

    Aside - last I read, ice baths are counterproductive to muscle growth because they reduce the inflamation that signals to growth. They’re useful for competitive scenarios where recovery is prime, but they don’t help with improvment. By all means keep doing it if you enjoy it. My strong preference is for a sauna!

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  • [–] [S] 1 point 9 hours ago

    The other area you can improve recovery and overall capacity with is performance enhancing drugs. That’s something I don’t really know too much about, but that’s the way I’ve heard it described - you heal faster, stronger.

    You're right and I'm so glad that thought hadn't even crossed my mind! Before this year, I planned to hop on testosterone through one of those "pill mill clinics" that advertise on facebook that operate in a legally gray area. But now I realize that if I took performance enhancing drugs (i.e. "gear" or TRT) then I would regret it, maybe not immediately but 5 or 10 or 20 years from now.

    Aside - last I read, ice baths are counterproductive to muscle growth because they reduce the inflamation that signals to growth. They’re useful for competitive scenarios where recovery is prime, but they don’t help with improvment. By all means keep doing it if you enjoy it. My strong preference is for a sauna!

    Indeed they are. I do them once per month now and in the middle of my de-load week. But when I first started, I did them weekly to build them into my identity as justified by the famous book "Atomic Habits" since an identity-based motivation lasts forever and doesn't drain mental resources compared to white-knuckling it.

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  • [–] 1 point 7 hours ago* (last edited 6 hours ago)

    "I pride myself on mental toughness so it’s not simply a matter of being lazy or cowardice." What? What does what you take pride in have to do with your performance? You could just be wrong. Your post gives the very strong impression of someone who's dramatically over thinking their training. If you're 40 and have been lifting for 10 months you probably literally don't know how hard you can push yourself, you haven't trained long enough or hard enough to have that experience.

    Why worry about minutiae like optimal weekly set range for hypertrophy or your mesolimbic neurotransmitters when you're a novice lifter? You aren't eating in a calorie range for optimal hypertrophy no matter what set range you are at. By your own report what you're doing is working so just keep it simple. Don't go looking for problems you don't have.

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