Plant sterols do lower cholesterol levels; replacing human cholesterol levels may be a better description of methodology. However there is no evidence that plant sterols reduce the risk of CHD and much evidence that they are detrimental.

It is time for us to remember that we are in the business of improving health outcomes and not surrogate endpoints. In losing sight of real targets, we can do more harm than good

Full Paper - https://doi.org/10.3844/ojbsci.2014.167.169