I got sick so bad I went from 220 pounds to 170 in five weeks. I had to look deep in to the drug records to find it. There was a very rare side effect that was below the threshold for reporting. It only occured in two people inthe trails. I finally found a forum where just two other people had this side effect. By that time I was on week four convinced I was going to die. They said their symptoms started to go away after the sixth week. Sure enough I finally could stand without throwing up and had a appetite in the sixth week of that hell.

The symptoms were persistent 24/7 nausea accompanied by dry heaves when I stood up.
No apetite at all. I had to force food down and if it was more complex than a cracker it came straight back up. This went on for six weeks. I went ten years before I nerved up enough to try another non stimulant ADHD med.