My wife and I bought an old house which has been rearranged many times over the years. One upstairs room has a sink, but no toilet or shower. The toilet is in a separate room with its own sink. It's the weirdest arrangement, but it works great.
We call it the toothbrush room. Most houses don't have such a room, but I do recommend it. It gets more use than most rooms. Obviously the entrance and kitchen gets the most use, but the whole family comes through the toothbrush room at least twice daily.
We've set some cabinets, make up mirrors, the ironing board, all the hair appliances and such. It's perfect for getting ready, ironing a shirt, flattening the hair, shaving or putting on makeup without having to stand in shit fumes or shower moist. It's the perfect ready room.