you are viewing a single comment's thread
view the rest of the comments
[–] 23 points 1 month ago (10 children)

A lot of money being wasted to find cures for mice. Maybe they should work on finding cures for people instead.

  • source
  • hideshow 10 child comments
  • [–] 18 points 1 month ago (2 children)

    I always thought that the /s was a stupid thing, but judging from the down votes on your comment, I guess it's a necessity

  • source
  • parent
  • hideshow 2 child comments
  • [–] 5 points 1 month ago

    They have a point. Mouse model research translation to human disease has a poor track record. Mouse model labs spin in circles between models and never try to translate into humans. Some diseases stall for decades in models.

    The mouse's brain plasticity is orders of magnitude higher than a human's.

  • source
  • parent
  • [–] 11 points 1 month ago (4 children)

    I spent a career in research and I can tell you that mice are excellent models for discovery, AMA

  • source
  • parent
  • hideshow 4 child comments
  • [–] 2 points 1 month ago (1 child)

    mice are excellent models for discovery

    Not really. What's the translate rate to humans? 9%?

    Mice can model some diseases well, but they are not universally good models.

  • source
  • parent
  • hideshow 1 child comment
  • [–] 5 points 1 month ago

    Not universal, for example we use zebrafish for spine defect models since mouse spine has an odd curve/hunch that doesn't line up as well. But for general metabolism/pathology/embryonic development they do a great job of mimicking human disease under the microscope. Its not always 1:1 but we learn a lot from these little guys.

  • source
  • parent