Let's get back to the beginning here. We were talking about Marxism-Leninism and how it is superior to vulgar empiricism and of course I've kept on with my original point from the beginning of using the scientific method to determine the best policies and political structures for governance, best in those that measurably increasing human wellbeing.
I guess you could bring in something like the double slit experiment and lot of esoteric science in which there isn't a clear way to tell which interpretation is the correct one or if it really maps to reality to begin with aka maybe the math works but that's not actually what's happening. Although I wouldn't see the connection between that and deciding how best to structure a city.
It really doesn't take much to see if people are healthy and happy, are prospering and living in a better state of being than they were before a policy was implemented.