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[Article] Male Birth Control Pill to Stop Sperm Production Passes Safety Test (www.scientificamerican.com)
submitted 5 months ago by to c/interestingshare@lemmy.zip
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A hormone-free pill, called YCT-529, that temporarily stops sperm production by blocking a vitamin A metabolite has just concluded its first safety trial in humans, getting a step closer to increasing male contraceptive options

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[–] 5 points 5 months ago (1 child)

Going several months with blocked vitamin A metabolism sounds like it'd lead to a vitamin deficiency of some kind.

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  • [–] 9 points 5 months ago

    The daily pill, called YCT-529, blocks a vitamin A metabolite from binding to its receptor in the testes; this action prevents the chain of gene-expression changes that are required to start the sperm-making process.

    It’s not supposed to effect the rest of the body, but I assume that’s one the side effects they’d be on the lookout for in this trial

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