The thing that shook me out of the existential crisis of understanding nihilism is that life had as much meaning before I was born as it will after my death.

Or in other words: we are the universe exploring itself - in playful exploration and/or aesthetic creation.

To me that gives license to do something interesting with the short time, resources and attention that I have available. I find experiencing new things or in new combinations fulfilling, as do I to help others make a positive contribution to the human experience (be it through positive societal change or practicing kindness).