Way too big of a broadcast domain. You'd start having perf issues if you were doing anything serious that would remotely come close to using even a fraction of the subnet.
I keep all my work stuff /22 or smaller typically. I struggle to see anyone needing anything more than /24 for home usage, and /23 for even the grandest of home lab setups if you didn't subnet anything. The amount of random shit broadcasting is pretty nuts.
My setups are often lazy. I usually use one subnet, set my dhcp server to only hand out things starting from .100 and never run out of static assignments that way. Using a separate subnet means all your shit has to go through a layer 3 device even if they're on an unmanaged switch or hub somewhere down the line.