Single psilocybin trip delivers two years of depression relief for cancer patients
(www.sciencedaily.com)
I'd like to offer the counterpoint that someone once advised me not to try weed until after I'd tried LSD, I followed that advice and I think it turned out for the better. There isn't exactly a benefit to being very impressed by the intensity of other drug experiences, and psychedelics can give you a sense of perspective about what you want out of life that's useful for navigating choices. They also tend to be self-deterring; you likely will feel more satisfied and grateful to have your feet on solid ground again after a trip, as opposed to immediately craving more, even if it was wonderful, which is a very convenient property many other drugs lack.