Fair question.

Example: The Philadelphia Incident, Bill Burr, 2005.

I don't think there's any such thing as an audience that objectively sucks. Humor is subjective, and I think there's a mental trap of "I think this joke is funny, therefore it is objectively funny and anyone who disagrees is just too stupid to get it" that some comedians fall into, especially if they have a small niche of people who also vibe with their brand of humor. But that attitude prevents you from critically analyzing why jokes are funny, why different things are funny to different audiences, why some jokes fit better in a riff while others can stand alone, etc. Humor is a collaborative craft and part of being good at it is being able to hear your audience say "no, not that one" and believe them.