Yes!

Don't do it, please.

It is dangerous to wear active noise cancelling headphones while driving.

It is dangerous to wear passive noise cancelling headphones while driving.

It is dangerous to wear any headphones (or earbuds) while driving.

And very likely illegal.

Yes. In many jurisdictions, it's illegal to use any kind of headphones while driving.

Many, many places it's illegal to drive with both ear buds in place. Thus, you'd never have "noise cancelling".

Don't!

It's dangerous to use anything that blocks your hearing, even just regular headphones!

It's dangerous to use headphones with active noise cancelling while walking. What do you think?

Yes. Anything that interferes with your ability to pay attention to keeping the tonnes of metal you’re driving on the road, is dangerous. It’s a distraction and stops you from being able to hear audio cues like sirens, crossing signals, etc. Horns are also not entirely “fuck you” buttons but to warn other drivers of potential hazards, through sound. Use your cars sound system. Buy a shitty dongle if you have to; but headphones of any variety is a bad idea for driving. It’s also illegal in some jurisdictions.

Yes.

That is the active removal of useful sensory information that pertains directly to driving.

VERY DANGEROUS.

It's illegal in many parts too

I remember back when I was taking driving lessons to get my learner's permit, they specifically said never to war headphones while driving. I don't know if it's illegal or just discouraged, but the intent is that it removes one of your senses from being able to help you react while driving. So it puts you and everyone around you on the road at risk.

If the problem is that your car is too loud, look into OTC hearing aids with active notice canceling. That way you can drown out the noise while still hearing important sounds.

my point is noise cancelation mitigates mostly monotone noise, it has hard time with anything you would need to pay attention to in a car

and i would argue "carefully listnening" to the racket going on in your car damages your hearing and you hear less longterm than using ear protection

People acting like noise canceling headphones block your hearing. Thats only if you listen to something on insane volume.

When I drive on highway I always have either earplugs or headphones, it mitigats wheel hum and wind noise. No way it blocks sirens, honking or even conversations.