The US health secretary, Robert F Kennedy Jr, faced the Senate finance committee in a tense and combative hearing on Thursday, during which lawmakers questioned his remarks expressing vaccine skepticism, claims that the scientific community is deeply politicized and the ongoing turmoil plaguing the Centers for Disease Control and Prevention (CDC).

In a hearing lasting more than three hours and ostensibly about the Trump administration’s healthcare agenda, Kennedy defended his leadership at the Department of Health and Human Services (HHS), claiming that his time at the agency will be focused on “unbiased, politics-free, transparent, evidence-based science in the public interest”.

Senate Democrats on the committee began the hearing calling for Kennedy’s resignation. “Robert Kennedy’s primary interest is taking vaccines away from Americans,” ranking member Ron Wyden, a Democratic senator from Oregon, said in his opening remarks. “People are hurt by his reckless disregard for science and the truth in this effort. I hope the very least, Robert Kennedy has the decency to tell the truth this morning.”