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An 80-year-old woman with late-stage Alzheimer's took 5g of psilocybin mushrooms, slept for 19 hours, woke up and started speaking again (www.microdos.in)
submitted 4 months ago by to c/warondrugs@feddit.uk
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A new case report published in Frontiers in Neuroscience describes an extraordinary but highly preliminary observation: an 80-year-old woman with advanced Alzheimer's disease showed temporary multidomain improvement after receiving a high dose of psilocybin-containing mushrooms.

Following administration of 5g of mushrooms, she entered a prolonged deep sleep-like state. After waking, she reportedly regained the ability to speak in full sentences, recognised family members, dressed independently, and recovered urinary continence after five years.

A later 3g dose appeared to extend some of these improvements.

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[–] 7 points 4 months ago (4 children)

5g seems like a LOT.

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  • [–] 6 points 4 months ago (2 children)

    Depending on the strain, it's not too uncommon of a dose to have a proper 'trip'.

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  • [–] 3 points 4 months ago (1 child)

    Yeah, originally I thought it said a 5g dose of psilocybin, and I was thinking Holy Crap. But then realized it said mushrooms, did a quick search and it said 3.5g.

    To be fair, I handle my drugs very badly. My local shop laughs at me because I am the only one they've ever had ask for "The weakest thing you have". So thinking at nearly 50% more than the "average" seems crazy to me.

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    • 12 comments in c/hackernews@lemmy.bestiver.se view that post
    [–] 10 points 4 months ago (2 children)

    Dude, what did she say?

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    • [–] 8 points 4 months ago

    Alzheimer's is definitely a weird one, it's common before death to have a period of lucidity, like full recovery territory. I don't pretend to understand why, but it stands to reason something that's going on is in some way reversable, maybe this tripped it? Hopefully it doesn't mean she's about to kark it.

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    [–] 5 points 4 months ago (1 child)

    Common Side Effects?

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    • [–] 4 points 4 months ago (2 children)

    The telephone chain with the headlines for the story are reaching the usual point of absurdity. The original stories about it were more realistic

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    • [+] -7 points 4 months ago (2 children)

    I hope she didn't say 'what the fuck man i did not consent to this trip' because that's what I would want to say. Mushrooms are on my never ever do list, I hope no one feeds them to me after I lose capacity.

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