Figuring out data centers in space is pretty much a prerequisite for any sort of significant transorbital flight
I don't think that's true. They seem like two separate problems.
AI datacenters use power at such magnitudes that trying to solve the cooling problem for that kind of satellite or ship might not be all that applicable to a ship occupied by living humans.
A data center satellite might be able to run hot to improve cooling characteristics. The Stefan-Boltzmann law makes radiators much more effective at higher temperatures. So maybe the solution there would involve building out chips and server components that can run hot, like above 90°C, with cooling systems designed to operate at those higher temperatures.
Meanwhile, it might be that the human occupied space stations will need to have temperatures that support human life, closer to 18°C. At the same time, why would a human occupied space station need megawatts of power, and the accompanying need to reject megawatts of waste heat?