are you using RT?

on my system the game crashes when loading into the game (or running benchmark) with RT on. Worked fine a month or two before the patch, I have no clue if some other update (proton-ge/cachy, heroic, nvidia-open, arch in general...) did it. Logs seem to indicate something about nvidia & shader compilation (I don't remember the exact error atm).

If it crashes straight from launch, check if you have your mods updated, eg. red4ext (winmm.dll) is really crash-happy if it's version doesn't match the game's

edit: oh derr, you got it fixed? gotta check the protondb then as well.