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[–] 3 points 3 weeks ago (1 child)

However, the study found compared to the placebo group:

  • Participants treated with semaglutide exhibited a broad pattern of slower biological aging across epigenetic clocks linked to inflammation and blood, brain, heart, kidney, liver and metabolic health.

  • The drug slowed the pace of biological aging by 9 %, as measured by the DunedinPACE epigenetic clock.

  • The drug significantly slowed biological processes associated with the risk of all‑cause mortality and age-related disease, as measured by the PCGrimAgeepigenetic clock.

It's just that the study focused on people with a particular condition so it takes more studies to know if it affects the general population similarly.

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  • [–] 3 points 3 weeks ago

    are these unique to the glp-1 intervention or are they echos of ketone production, fat metabolism, increased insulin sensitivity... are there more effective ways to achieve the same marker improvements without using a glp-1? (obviously yes)

    Making casual claims like slow biological aging requires the context which the data is based, and a demonstration of the mechanisms.

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