Ditto for Smalltalk and Lisp.

Squeak Smalltalk and its evolutions, Pharo and Cuis, get talked up for being easy to program and re-program, but the closest to being a useful app is recent: the DrGeo rewrite. Others like Glamorous Toolkit and various proprietary developments with Cuis don't lead to any useful outcome.

Lisp with its macrology is deified, but its most used variant, Elisp in Emacs, is confounding in terms of comprehending the runtime behaviour of features and in the debugging of what doesn't work. Guile Scheme has so much written about it, but Guix is just about its only success.