Focus follows mouse and unchecking the option to auto raise the active window. Couldn't live without it and being used to it has made me extremely clumsy when I do pick up my Windows work laptop.

I change the taskbar clock to be a one-line MM/DD HH:MM:SS format, drop in my customized locale (based on en-US for maximum compatibility, but without having to deal with US formats and units that I'm not fond of), and point the taskbar shortcut for my text editor to a script that creates a pre-named file and launches the editor with autosave enabled. Because having to manually save and come up with a name for your spur-of-the-moment notes sucks, automatically generating 20260831_text_1 is so much better than a, b, a2, etc.

XFCE specific, I get rid of the second panel full of launchers. Acquired taste, but also Chicago95 theme and icon pack.