I could see that being the case I suppose. The anus is full of blood vessels, and boofing gets it straight to the blood stream instead of breaking down into metabolites in the digestive system. Just very different than any hormone therapy I’ve heard of, for like menopause and stuff. Tho that could just be that old rich white women won’t stick fingers up the bum..

Now I wonder if ftm have something similar that gets vaginally inserted (only non-oral hole with more blood vessels than the anus is the vagina!)

Thanks for the info, I feel more informed :)