I'm not very far in yet but it doesn't seem especially hard. You can change the difficulty as well.

God Hand has a dynamic scaling difficulty system akin to Resident Evil 4 (same director). The better you are at the game the tougher it gets. That said, the baseline level of difficulty is reflex-heavy & rewards careful observation of enemy attacks. Persistent players can get through most challenges, with the boss fights being the hardest barriers. I would compare the difficulty to Sekiro in 1:1 fights, the fights become this careful dance where one mistake can kill you. Hella fun if you're into it.