Depends a lot on the engine or even just the timing.

My 2023 can ramp up and down power by analysing various signals.

I had an old sports car that could detect knock and pull timing but that was about it. Waiting until it knocks isn’t super healthy.

I have an old truck that I could set timing using high octane and get some better efficiency out of it, but I’d rather it be able to run on a mix of sewer runoff and coyote piss so it’s timing is pretty forgiving.