Not really. The state of the art models are huge, even the open-weight ones. You really don't want to quantize below 4-bit, and even that's a bit of a stretch... Ideally you'd use at least 8-bit to get good results with these models when used for coding.

GLM-5.1 needs around 400GB VRAM at 4-bit quantization. Apple aren't making the Mac Studio with 512GB unified RAM any more, so you'd need something like 5 x Nvidia A100 80GB to run a model like this.

Kimi K2.6 is around the same size.