“Keeping with the idea of the brain as a sponge, we also thought of it as a dirty sponge — how do you clean a dirty sponge?” Costanzo asked.

“You run it under a tap and squeeze it out. In our simulations, we were able to get a sense of how the brain moving from an abdominal contraction can help induce fluid flow over the brain to help clear waste products.” > Maybe those crackpots like Kellogg, with their laxative obsession, were (almost) onto something.