Well, technically there's Vampire: The Requiem. It's very similar, but not in the exact same universe. Some of the names are reused, but there's no canon metaplot, and many details are changed. I personally liked it a lot, but I think it's less popular than Masquerade.

If you want to roll your own setting, I bet there are generic systems that would work. Fate is my go-to, and I can see how it would work. (Probably a stress track for hunger, some consequence boxes for becoming a monster)