What worked for me was to make sure to eat while taking it (within a 20 min window - could do 40 but that was pushing it), and go for a short run a 40-60 min after taking it.

Having my heart rate already up when it kicked in made the heartrate spike barely noticeable, and it felt like I burned through the side effects just by suffering through a run for 15-20 min. I guess biking or any cardio training could have the same effect, but running was easiest for me to fit into my schedule.