A lot of the nicotine in products like these is made from tobacco. Some of it is synthetic nicotine, some is plant-derived.
I couldn’t find statistics but at least some companies have different product names for synthetic vs natural.
e.g. “VELO” is plant-derived while “VELO Plus” is synthetic.
https://nicokick.com/us/pouch-perfect/products/velo-vs-velo-plus