Pacing yourself is key. As you get tipsy and feel good, the tendency will be to feel "yeah, let's have another and feel this even more!" and to drink more before what you've already drank has taken effect.
Drinks on an empty stomach will hit you faster. And be more likely to upset your stomach. Drinking with food is generally a better experience, but because this slows your absorbtion, you need to pace yourself even more.
But if the drinking does get away from you and you start to feel sick, let yourself throw up. You will feel better for it.